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首页> 外文期刊>Hormone research >Sudden death in Prader-Willi syndrome: brief review of five additional cases. Concerning the article by U. Eiholzer et al.: Deaths in children with Prader-Willi syndrome. A contribution to the debate about the safety of growth hormone treatment in children with PWS (Horm Res 2005;63:33-39).
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Sudden death in Prader-Willi syndrome: brief review of five additional cases. Concerning the article by U. Eiholzer et al.: Deaths in children with Prader-Willi syndrome. A contribution to the debate about the safety of growth hormone treatment in children with PWS (Horm Res 2005;63:33-39).

机译：普拉德-威利综合症突然死亡：另外五个病例的简要回顾。关于U. Eiholzer等人的文章：Prader-Willi综合征儿童死亡。对有关PWS儿童生长激素治疗安全性辩论的贡献（Horm Res 2005; 63：33-39）。

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摘要

Growth hormone (GH) has been used for the treatment of children with Prader-Willi syndrome (PWS) for at least 20 years . The referral of PWS children to pedi-atric endocrinologists has resulted, in many regions and countries, in a consolidation of the care of PWS patients by a small group of physicians. This includes enrollment into GH safety databases, and together, these sources may provide a new window into the natural history of this condition both with and without GH treatment. Over the last few years there have been a number of reports of sudden death in PWSpatients without GH treatment [2-4]. Sudden death was first reported in association with GH in 2002 with reports of 2 patients .
机译：生长激素（GH）已用于治疗患有Prader-Willi综合征（PWS）的儿童至少20年了。在许多地区和国家，将PWS儿童转诊给儿科内分泌科医生已导致一小部分医生加强了对PWS患者的护理。这包括注册到GH安全性数据库中，并且这些来源一起可能为了解是否接受GH治疗的这种疾病的自然病史提供新的窗口。在过去的几年中，有许多报道称未经GH治疗的PWS患者突然死亡[2-4]。 GH于2002年首次报道猝死，2例患者死亡。

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