...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Development >Mammary development in the embryo and adult: a journey of morphogenesis and commitment.
【24h】

Mammary development in the embryo and adult: a journey of morphogenesis and commitment.

机译：胚胎和成年哺乳动物的乳腺发育：形态发生和定型的旅程。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Mammary gland development occurs through distinctive stages throughout embryonic and pubertal development and reproductive life. At each stage, different signals are required to induce changes in both the epithelium and the surrounding mesenchyme/stroma. Recent studies have provided new insights into the origin, specification and fate of mammary stem and progenitor cells and into how the differentiated lineages that comprise the functional mammary gland are determined. The development of new tools and culture techniques has also enabled the factors that influence branching morphogenesis in the embryonic and pubertal gland to be identified. A surprising recent discovery has been that mammary epithelial cells commit to differentiated lineages using the same signalling pathways that regulate lineage determination in T helper cells.
机译：乳腺发育通过胚胎和青春期发育以及生殖生命的不同阶段发生。在每个阶段，需要不同的信号来诱导上皮和周围的间充质/基质的变化。最近的研究为乳腺干细胞和祖细胞的起源，规格和命运以及如何确定组成功能性乳腺的分化谱系提供了新的见识。新工具和培养技术的发展也使得能够确定影响胚胎和青春期分支形态发生的因素。最近一个令人惊讶的发现是，乳腺上皮细胞使用调节T辅助细胞中谱系确定的相同信号通路，致力于分化的谱系。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号