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首页> 外文期刊>Developmental Medicine and Child Neurology >Hyoscine skin patches for drooling dilate pupils and impair accommodation: spectacle correction for photophobia and blurred vision may be warranted.
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Hyoscine skin patches for drooling dilate pupils and impair accommodation: spectacle correction for photophobia and blurred vision may be warranted.

机译：用于流口水的瞳孔皮肤斑块会扩大瞳孔并损害住宿能力：可能需要矫正眼镜以防畏光和视力模糊。

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Hyoscine skin patches diminish salivation by their anticholinergic action. The aim of reporting this case series is to present the ophthalmic side effects in children, and to highlight the precautions to take. Five children (two males, three females; age range 8-18y) with quadraplegic cerebral palsy (Gross Motor Function Classification System Level V) and profound intellectual impairment, wearing hyoscine skin patches to control excessive salivation, were examined. Binocular visual acuity, pupil reaction, pupil diameter, and dynamic retinoscopy were recorded before and after instilling guttae cyclopentolate 1%. The accommodative responses were compared with the expected norms. Spectacle correction was provided for refractive error and to compensate for lack of accommodation. Tinted lenses were provided for photophobia. Visual assessment was repeated 6 months later. All children had dilated pupils with a mean diameter of 7.8mm (range 7-9mm) before instilling guttae cyclopentolate. Mean pupil constriction to bright light was only 1.8mm (range 1-2mm). Mean resting accommodation was 0.45 dioptres (D; range 0-1D) and no accommodative responses were detected on dynamic retinoscopy. Three children were photophobic. Visual behaviour was seen to improve after the use of appropriate spectacles. Photophobia was relieved by tinted lenses. The anticholinergic effects of hyoscine skin patches can cause photophobia and impair vision due to pupil dilatation and paralysis of accommodation. Appropriate spectacles are recommended.
机译：Hyscine皮肤斑块通过其抗胆碱能作用减少了唾液分泌。报告该病例系列的目的是介绍儿童的眼部副作用，并强调要采取的预防措施。检查了五名患有四肢瘫痪性脑瘫（严重运动功能分类系统V级）且智力严重受损，穿有雾化皮肤斑块以控制过多唾液分泌的儿童（两名男性，三名女性;年龄在8-18岁之间）。滴注1％戊二醇环戊酸酯前后，记录双眼视力，瞳孔反应，瞳孔直径和动态检影。调节反应与预期标准进行了比较。眼镜矫正是为了矫正屈光不正并弥补缺乏适应性。提供有色镜片以防畏光。 6个月后重复视觉评估。所有儿童在滴入环戊四烯酸胍之前，瞳孔平均直径为7.8mm（范围为7-9mm）。平均瞳孔对强光的收缩只有1.8mm（范围为1-2mm）。平均静息适应度为0.45屈光度（D;范围0-1D），动态检影未检测到调节反应。三个孩子怕光。使用适当的眼镜后，视觉行为得到改善。有色镜片缓解了恐惧症。由于瞳孔扩张和住宿瘫痪，发烟样皮肤贴剂的抗胆碱作用可能导致畏光和视力受损。建议佩戴合适的眼镜。

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