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首页> 外文期刊>Diabetic medicine: A journal of the British Diabetic Association >Quality of life after islet transplantation: data from the GRAGIL 1 and 2 trials.
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Quality of life after islet transplantation: data from the GRAGIL 1 and 2 trials.

机译：胰岛移植后的生活质量：来自GRAGIL 1和2试验的数据。

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BACKGROUND: Rigorous assessment of health-related quality of life (HRQL) is mandatory to establish the benefits of islet transplantation. METHODS: The 36-Item Short Form Health Survey (SF-36) and the Diabetes Quality of Life (DQOL) scales were completed by patients included in an Islet Transplantation Alone (ITA) trial (n = 10) and an Islet After Kidney (IAK) trial (n = 10). RESULTS: The two populations differed by HRQL scores at baseline, with poorer scores in ITA patients. SF-36 scores for physical limitations, bodily pain, general health perception, social functioning, and health transition improved significantly in ITA patients 6 and 12 months post transplantation. The DQOL global score was significantly improved at 6 months and remained so at 12 months, because of a significant improvement in the dimensions of satisfaction and impact of diabetes. No improvement was observed in the IAK patients. CONCLUSION: HRQL assessment may help in the selection of candidates with brittle diabetes for islet transplantation.
机译：背景：必须严格评估与健康相关的生活质量（HRQL），以建立胰岛移植的益处。方法：36项简短健康调查表（SF-36）和糖尿病生活质量（DQOL）量表由单独进行胰岛移植（ITA）试验（n = 10）和经肾脏移植后胰岛的患者完成（ IAK）试用（n = 10）。结果：这两个人群在基线时的HRQL评分有所不同，ITA患者的评分较差。移植后6个月和12个月的ITA患者，SF-36的身体局限性，身体疼痛，总体健康感知，社会功能和健康过渡得分明显提高。 DQOL总体评分在6个月时显着改善，而在12个月时仍保持这一水平，因为在满意度和糖尿病影响方面有了显着改善。在IAK患者中未观察到改善。结论：HRQL评估可能有助于选择脆性糖尿病患者进行胰岛移植。

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