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首页> 外文期刊>Diabetic medicine: A journal of the British Diabetic Association >Impact of diabetes and gender on survival after acute myocardial infarction in the Province of Quebec, Canada--a population-based study.
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Impact of diabetes and gender on survival after acute myocardial infarction in the Province of Quebec, Canada--a population-based study.

机译：一项基于人群的研究，加拿大魁北克省糖尿病和性别对急性心肌梗塞后存活的影响。

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AIMS: To examine the impact of diabetes, gender and their interaction on 30-day, 1-year and 5-year post-acute myocardial infarction (AMI) mortality in three age groups (20-64, 65-74 and > or = 75 years). METHODS: Retrospective analysis including 23 700 patients aged > or = 20 years (22% with diabetes) admitted to hospital for a first AMI in any hospital in the Province of Quebec, Canada, between April 1995 and March 1997. Administrative databases were used to identify patients and assess outcomes. RESULTS: Regarding 30-day mortality, there was non-significant interaction between diabetes and gender. Women aged < 75 years had, independently of diabetes status, at least a 38% (P < 0.05) higher mortality than their male counterparts after adjustment for socio-economic status and co-morbid conditions. Gender difference disappeared, however, after controlling for in-hospital complications. Regarding 1-year mortality (31-365 days), there was no significant gender disparity for all age groups. During the 5-year follow-up, no gender differences were seen in any age group, except for younger (< 65 years) women with diabetes, who had a 52% (P = 0.004) higher mortality than men after controlling for co-variables. This female disadvantage was demonstrated by a significant interaction between diabetes and gender in patients aged < 65 years (P = 0.009). CONCLUSIONS: The higher 30-day mortality post-AMI in younger (20-64 years) and middle-aged (65-74 years) women compared with men was not influenced by diabetes status. However, during the 5-year follow-up, the similar gender mortality observed in patients without diabetes seemed to disappear in younger patients with diabetes, which may be explained by the deleterious, long-term, post-AMI impact of diabetes in younger women.
机译：目的：研究三个年龄段（20-64岁，65-74岁和≥=）的糖尿病，性别及其相互作用对急性后30天，1年和5年心肌梗死（AMI）死亡率的影响75年）。方法：回顾性分析包括1995年4月至1997年3月在加拿大魁北克省任何一家医院接受首次AMI治疗的23700名年龄≥20岁（22％患有糖尿病）的患者。识别患者并评估结果。结果：关于30天死亡率，糖尿病与性别之间无显着相互作用。调整了社会经济状况和合并症后，年龄<75岁的女性的死亡率与男性状况相比，至少比男性高38％（P <0.05）。但是，在控制了院内并发症后，性别差异消失了。关于1年死亡率（31-365天），所有年龄段的男女均无明显差异。在为期5年的随访中，除年龄较小（<65岁）的女性糖尿病患者（在控制性合并糖尿病后，其死亡率比男性高52％）（P = 0.004）外，任何年龄组均未发现性别差异。变量。 <65岁的患者中，糖尿病与性别之间的显着相互作用证明了这种女性劣势（P = 0.009）。结论：与男性相比，年轻（20-64岁）和中年（65-74岁）女性的AMI后30天死亡率较高。然而，在5年的随访中，年轻的糖尿病患者在无糖尿病患者中观察到的相似的性别死亡率似乎消失了，这可以由年轻女性对AMI的长期有害糖尿病影响来解释。 。

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