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首页> 外文期刊>Diagnostic and therapeutic endoscopy >Clinical Application and Outcomes of Over the Scope Clip Device: Initial US Experience in Humans.
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Clinical Application and Outcomes of Over the Scope Clip Device: Initial US Experience in Humans.

机译：Scope Clip设备的临床应用和结果：美国人类的初步经验。

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Background. OTSCs are now available in the US for various indications. Methods. Retrospective review of OTSCs used from January 2011 to April 2012. Results. Twenty-four patients underwent placement of 28 OTSCs. Indications included postsurgical fistula, perforations, anastomotic leak, prophylactic closure after EMR, postpolypectomy bleeding, tracheoesophageal fistula, and jejunostomy site leak. Instruments used to grasp the tissue were dedicated (bidirectional forceps or tripronged device) and nondedicated devices (rat/alligator forceps or suction). Success was higher with nondedicated devices (12.5% versus 86.5%, P = 0.0004). Overall, OTSC was effective in 15/27 procedures. Defect closure was complete in 12/21. Mean followup was 2.9 months (1-8 m). Mean defect size was 10 mm (5-25 mm). A trend towards higher success was noted in defects <10 mm compared to defects >10 mm (90% versus 60%; P = 0.36). No difference was noted in closure of fresh (<72 hrs) versus chronic defects (>1 month) (75% versus 67%). There were no complications. Conclusion. The OTSC provides a safe alternative to manage fistula, perforation, and bleeding. No significant difference was seen for closure of early fistula or perforations as compared to chronic fistula. Rat-tooth forceps or suction was superior to the dedicated devices.
机译：背景。 OTSC现在在美国可以用于各种适应症。方法。对2011年1月至2012年4月使用的OTSC的回顾性审查。结果。 24例患者接受了28例OTSC。适应症包括手术后瘘管，穿孔，吻合口漏，EMR后预防性闭合，息肉切除术后出血，气管食管瘘和空肠造口部位漏气。用于抓取组织的器械是专用的（双向镊子或三叉器械）和非专用的器械（大鼠/配子钳或吸管）。非专用设备的成功率更高（12.5％对86.5％，P = 0.0004）。总体而言，OTSC在15/27程序中有效。缺陷闭合在12/21中完成。平均随访时间为2.9个月（1-8 m）。平均缺陷尺寸为10毫米（5-25毫米）。与小于10 mm的缺陷相比，小于10 mm的缺陷有更高的成功趋势（90％比60％; P = 0.36）。新鲜闭合（<72小时）与慢性缺陷（> 1个月）的闭合率没有差异（75％对67％）。没有并发症。结论。 OTSC提供了一种安全的替代方法来处理瘘管，穿孔和出血。与慢性瘘管相比，早期瘘管或穿孔的闭合无明显差异。鼠齿钳或吸力优于专用设备。

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