...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Diagnostic cytopathology >Small Cell Mesothelioma: A Rare Entity and Diagnostic Pitfall Mimicking Small Cell Lung Carcinoma on Fine-Needle Aspiration
【24h】

Small Cell Mesothelioma: A Rare Entity and Diagnostic Pitfall Mimicking Small Cell Lung Carcinoma on Fine-Needle Aspiration

机译：小细胞间皮瘤：细针穿刺模仿小细胞肺癌的罕见实体和诊断陷阱。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Small cell mesothelioma (SCM) is an extremely rare variant of epithelioid mesothelioma that can be mistaken for other forms of small round blue cell tumors, particularly small cell lung carcinoma (SCLC). Here, we describe a fine-needle aspiration (FNA) from a pleural lesion in a 75-year-old man with a history of known asbestos exposure. The FNA revealed cohesive clusters of uniform small round blue cells with high nuclear-tocytoplasmic ratio, finely powdery chromatin, small inconspicuous nucleoli, and scant amount of cytoplasm. Mitoses were infrequent and nuclear molding was absent. Immunochemical profile supported a mesothelial origin, which was later confirmed by pleurectomy with a diagnosis of SCM. This report demonstrates the difficulties in cytologic evaluation of lung FNAs in differentiating SCM from SCLC or other small round blue cell tumors. As therapy differs for SCM, early recognition of the cytologic features is essential in making the correct diagnosis needed for appropriate clinical management. (C) 2016 Wiley Periodicals, Inc.
机译：小细胞间皮瘤（SCM）是上皮样间皮瘤的一种极为罕见的变体，可被误认为是其他形式的小圆形蓝细胞瘤，特别是小细胞肺癌（SCLC）。在这里，我们描述了一名75岁男性的胸膜病变细针穿刺术（FNA），该患者有已知的石棉暴露史。 FNA揭示了均匀的小圆形蓝色细胞的凝聚簇，其具有高的核-细胞质比率，细粉状的染色质，小的不显眼的核仁和少量的细胞质。线粒体很少见，没有核成型。免疫化学特征支持了间皮起源，后来被胸膜切除术确诊为SCM。该报告证明了在区分SCM与SCLC或其他小圆形蓝细胞肿瘤方面，肺FNA的细胞学评估困难。由于SCM的治疗方法不同，因此，对细胞学特征进行早期识别对于做出适当的临床治疗所需的正确诊断至关重要。 （C）2016威利期刊公司

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号