Glucose restriction: longevity SIRTainly, but without building muscle?

Canto C; Auwerx J

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Glucose restriction: longevity SIRTainly, but without building muscle?

机译：葡萄糖限制：长寿SIR很好，但是却没有肌肉？

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The two metabolic sensors AMPK and SIRT1 take center stage as Fulco et al. reveal, in this issue of Developmental Cell, the signaling mechanism by which low glucose prevents the correct development of the myogenic program. These observations may hold some therapeutic promise against muscle wasting.

机译：与Fulco等人一样，两个代谢传感器AMPK和SIRT1占据了中心位置。在本期《发育细胞》中揭示了低葡萄糖阻止肌原性程序正确发育的信号传导机制。这些观察结果可能对防止肌肉萎缩具有治疗前景。

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《Developmental cell》 |2008年第5期|共3页
作者
Canto C; Auwerx J;
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正文语种 eng
中图分类普通生物学;
关键词
Animals; Cytokines; Enzyme Activation; Glucose; Longevity; Mice; Multienzyme Complexes; 动物; 细胞活素类; 酶激活; 葡萄糖; 长寿; 小鼠; 多酶复合物; 蛋白质丝氨酸苏氨酸激酶;

机译：Animals;Cytokines;Enzyme Activation;Glucose;Longevity;Mice;Multienzyme Complexes;动物;细胞活素类;酶激活;葡萄糖;长寿;小鼠;多酶复合物;蛋白质丝氨酸苏氨酸激酶;

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1. Glucose restriction: longevity SIRTainly, but without building muscle? [J] . Canto C, Auwerx J Developmental cell . 2008,第5期

机译：葡萄糖限制：长寿SIR很好，但是却没有肌肉？
2. Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle. [J] . Park S, Komatsu T, Hayashi H, Experimental Gerontology . 2006,第9期

机译：在中年开始的热量限制可以改善葡萄糖耐量，而不会影响大鼠骨骼肌中与年龄相关的胰岛素信号传导障碍。
3. Preventing the calorie restriction-induced increase in insulin-stimulated Akt2 phosphorylation eliminates calorie restriction's effect on glucose uptake in skeletal muscle [J] . SharmaN., AriasE.B., SequeaD.A., Biochimica et biophysica acta. Molecular basis of disease: BBA . 2012,第11期

机译：防止卡路里限制引起的胰岛素刺激的Akt2磷酸化增加，消除了卡路里限制对骨骼肌葡萄糖摄取的影响
4. Elemental Composition of Atmospheric Particles during Periods with and without Traffic Restriction in Beijing: The Effectiveness of Traffic Restriction Measure [C] . Renjian Zhang, Zhenxing Shen, Leiming Zhang, Proceedings of the 7th Asian aerosol conference . 2011

机译：北京有无交通限制时段大气颗粒物的元素组成：交通限制措施的有效性
5. The Effects of Glucose and Amino Acid Restriction on Protein Turnover and Micro-RNA Composition in the Muscle of Rainbow Trout [D] . Latimer, Mary Neslund. 2018

机译：葡萄糖和氨基酸限制对彩虹鳟鱼肌蛋白质周转和微RNA组成的影响
6. Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise [O] . Haiyan Wang, Naveen Sharma, Edward B. Arias, -1

机译：30个月大大鼠热量受限（无论是否进行剧烈运动）后的比目鱼肌中的胰岛素信号传导和葡萄糖摄取
7. Glucose restriction: longevity SIRTainly, but without building muscle? [O] . Cantó, Carles, Auwerx, Johan 2008

机译：葡萄糖限制：长寿SIR很好，但是却没有肌肉？

Glucose restriction: longevity SIRTainly, but without building muscle?

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