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首页> 外文期刊>Digestive Diseases and Sciences >Inflammatory bowel disease characteristics and treatment in Hispanics and Caucasians.
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Inflammatory bowel disease characteristics and treatment in Hispanics and Caucasians.

机译:西班牙裔人和高加索人的炎症性肠病特征和治疗。

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BACKGROUND: Many inflammatory bowel disease (IBD) studies have focused on Caucasian patients and little data exist on IBD in Hispanics living in the United States. AIM: The aim of our study was to compare IBD characteristics between Hispanic and Caucasian patients in the Harris County Hospital District (HCHD). METHODS: We identified patients within the HCHD with a diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) recorded during 2000-2006. Primary medical record review was performed to confirm the diagnosis and to abstract data on patient demographics, disease characteristics and treatment. RESULTS: A total of 69 Hispanic and 83 Caucasian patients with confirmed IBD were analyzed. Hispanics were diagnosed with IBD at an older age than Caucasians (mean age 37.8 SD 16 vs. mean age 29.0 SD 14, P < 0.01). In Hispanics with IBD, there was a lower proportion of patients with CD compared to Caucasians with IBD (36% vs. 65%, P < 0.01). Although there were no significant differences in diagnostic examinations or medication prescription between the two groups, there was a higher number of bowel resections per patient in Caucasians compared with Hispanics (0.5 vs. 0.22, P = 0.01). CONCLUSIONS: Hispanics with IBD were diagnosed at a significantly older age than Caucasians and had a lower number of bowel resections per patient. In Hispanics with IBD, UC was more common than CD while CD was more common than UC among Caucasians with IBD. Further research is required to confirm these observations and determine if these findings reflect genetic or environmental differences.
机译:背景:许多炎症性肠病(IBD)研究都集中在白人患者上,而居住在美国的西班牙裔人关于IBD的数据很少。目的:我们的研究目的是比较哈里斯县医院区(HCHD)的西班牙裔和高加索患者的IBD特征。方法:我们在HCHD中鉴定了2000-2006年期间诊断为克罗恩病(CD)或溃疡性结肠炎(UC)的患者。进行了初步病历审查,以确认诊断并提取有关患者人口统计学,疾病特征和治疗的数据。结果:共分析了69名西班牙裔患者和83名确诊IBD的白人患者。西班牙裔人被诊断出患有IBD的年龄比白种人高(平均年龄37.8 SD 16 vs.平均年龄29.0 SD 14,P <0.01)。与IBD的白种人相比,IBD的西班牙裔患者中CD患者的比例更低(36%比65%,P <0.01)。尽管两组之间的诊断检查或药物处方没有显着差异,但与西班牙裔相比,高加索人均每例患者的肠切除术次数更高(0.5 vs. 0.22,P = 0.01)。结论:被诊断为IBD的西班牙裔患者被诊断出比白种人高得多的年龄,并且每位患者的肠切除术次数更少。在患有IBD的西班牙裔中,UC比CD更普遍,而CDD在IBD的白种人中比UC更普遍。需要进一步的研究来确认这些观察结果,并确定这些发现是否反映了遗传或环境差异。

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