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Early versus traditional postoperative oral feeding in patients undergoing elective colorectal surgery: A meta-analysis of randomized clinical trials

机译：择期结直肠手术患者术后早期和传统的口服口服喂食：一项随机临床试验的荟萃分析

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Background: The safety and effectiveness of early oral feeding after colorectal surgery has not been determined. We performed a meta-analysis to evaluate surgical outcomes following early oral feeding compared with traditional oral feeding in patients undergoing elective colorectal surgery. Methods: MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched to identify randomized clinical trials comparing the outcomes following early oral feeding versus traditional oral feeding in patients undergoing elective colorectal surgery. The trials must have reported at least one of the following end points: anastomotic dehiscence, pneumonia, wound infection, nasogastric tube reinsertion, vomiting, mortality, length of hospital stay, hospital costs, and quality of life. Results: Seven trials, which included a total of 587 patients, met our inclusion criteria. Compared with traditional oral feeding, early oral feeding reduced the length of hospital stay (weighted mean difference -1.58 days; 95% CI -2.77 to -0.39; p = 0.009) and the total postoperative complications (relative risk 0.70; 95% CI 0.50-0.98; p = 0.04). There were no significant differences in the risk of anastomotic dehiscence, pneumonia, wound infection, rate of nasogastric tube reinsertion, vomiting, or mortality. Conclusions: Early oral feeding is safe and effective in patients undergoing elective colorectal surgery.
机译：背景：结直肠手术后早期口服喂养的安全性和有效性尚未确定。对于进行选择性结直肠手术的患者，我们进行了一项荟萃分析以评估早期口服喂养与传统口服喂养相比的手术效果。方法：检索MEDLINE，EMBASE和对照试验的Cochrane中央登记册，以识别随机临床试验，比较接受择期结直肠手术的患者早期口服喂养与传统口服喂养后的结果。该试验必须至少报告以下终点之一：吻合口裂开，肺炎，伤口感染，再次插入鼻胃管，呕吐，死亡率，住院时间，住院费用和生活质量。结果：共有587名患者的7项试验符合我们的纳入标准。与传统的口服喂养相比，早期口服喂养减少了住院时间（加权平均差-1.58天; 95％CI -2.77至-0.39; p = 0.009）和术后总并发症（相对危险度0.70; 95％CI 0.50） -0.98; p = 0.04）。吻合口裂，肺炎，伤口感染，鼻胃管再插入率，呕吐或死亡的风险没有显着差异。结论：早期口服喂养对于结直肠癌择期手术是安全有效的。

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