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首页> 外文期刊>Drug discovery today >Placebo: new insights into an old enigma.
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Placebo: new insights into an old enigma.

机译：安慰剂：对旧谜的新见解。

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Our understanding of the placebo effect has deepened through intensive research activity during recent years. It seems important to make a clear distinction between the placebo effect in clinical trials and the placebo effect in clinical practice. In the first scenario, our effects are directed towards minimising its influence on the results whereas, in the second scenario, we might consider maximising it for the benefit of the patient. It also seems important to differentiate between the 'true' and the 'perceived' placebo effect. The 'perceived' placebo effect equals the 'true' placebo effect plus a multitude of other factors. This article reviews new research on the mechanisms of placebo effects, discusses the role of placebos in clinical trials and explores the place of placebo in clinical practice. It concludes that a better understanding of this area will probably benefit basic research, clinical research and patient care.
机译：近年来，通过深入的研究活动，我们对安慰剂作用的了解加深了。明确区分临床试验中的安慰剂效果和临床实践中的安慰剂效果似乎很重要。在第一种情况下，我们的效果旨在将其对结果的影响最小化，而在第二种情况下，我们可以考虑将其最大化以使患者受益。区分“真实”和“感知”安慰剂效应似乎也很重要。 “感知的”安慰剂效应等于“真实的”安慰剂效应加上许多其他因素。本文回顾了有关安慰剂作用机理的新研究，讨论了安慰剂在临床试验中的作用，并探讨了安慰剂在临床实践中的地位。结论是，对这一领域的更好理解可能会有益于基础研究，临床研究和患者护理。

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