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首页> 外文期刊>Drug discovery today >Advancing drug discovery through systems biology.
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Advancing drug discovery through systems biology.

机译:通过系统生物学促进药物发现。

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摘要

Pharmaceutical companies are facing an urgent need to both increase their lead compound and clinical candidate portfolios and satisfy market demands for continued innovation and revenue growth. Here, we outline an emerging approach that attempts to facilitate and alleviate many of the current drug discovery issues and problems. This is, in part, achieved through the systematic integration of technologies, which results in a superior output of data and information, thereby enhancing our understanding of biological function, chemico-biological interactions and, ultimately, drug discovery. Systems biology is one new discipline that is positioned to significantly impact this process.
机译:制药公司迫切需要增加其领先的化合物和临床候选药物组合,并满足市场对持续创新和收入增长的需求。在这里,我们概述了一种新兴的方法,试图促进和缓解许多当前的药物发现问题。这部分是通过技术的系统集成来实现的,从而带来了卓越的数据和信息输出,从而增强了我们对生物学功能,化学生物学相互作用以及最终药物发现的理解。系统生物学是一门新学科,旨在显着影响这一过程。

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