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Biologics and postbiologics: novel immunotherapeutics for the induction and maintenance of remission.

机译:生物制品学和生物制品学:用于诱导和维持缓解的新型免疫疗法。

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摘要

Rapid growth in the development of new tools and advances in molecular immunology has led to a class of drugs called biologics. While effective, these therapies are costly, typically require continuous administration and often have serious side effects. This review focuses on current therapies and the need for a new class of therapies. A novel class of drugs able to induce and maintain tolerance will be paralleled with the notion that combination therapy appropriately tailored to patient subpopulations may hold the promise of less costly and more effective therapy.
机译:随着新工具的发展和分子免疫学的飞速发展,产生了一种称为生物制剂的药物。尽管有效,但是这些疗法昂贵,通常需要连续施用并且经常具有严重的副作用。这篇综述着重于当前的疗法以及对新型疗法的需求。能够诱导和维持耐受性的一类新型药物将与以下概念相平行:适当地针对患者亚人群量身定制的联合疗法可能有望实现成本更低且更有效的疗法。

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