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首页> 外文期刊>Drug discovery today >Calcium phosphate biomaterials as bone drug delivery systems: a review.
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Calcium phosphate biomaterials as bone drug delivery systems: a review.

机译:磷酸钙生物材料作为骨给药系统的研究。

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摘要

A short review is proposed on the existing literature for the research performed in calcium phosphate (CaP) biomaterials used as drug delivery systems. In the first part, a brief update is given on the performance of both CaP ceramics and CaP cements. Second, a review of the research and clinical situation is developed for CaP materials already used as drug delivery systems. Experimental works performed for local delivery are reported. In particular, a description is given of the in vitro and in vivo studies in which these materials are loaded with various proteins and drugs.
机译:对于在现有文献中对用作药物输送系统的磷酸钙(CaP)生物材料进行的研究提出了简短的评论。在第一部分中,简要介绍了CaP陶瓷和CaP水泥的性能。其次,对已经用作药物递送系统的CaP材料进行了研究和临床情况的综述。报告了为当地交付进行的实验工作。特别地,给出了体外和体内研究的描述,其中这些材料中装载了各种蛋白质和药物。

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