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首页> 外文期刊>Drug and alcohol review >Comorbid attention deficit hyperactivity disorder and substance use disorder complexity and chronicity in treatment-seeking adults
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Comorbid attention deficit hyperactivity disorder and substance use disorder complexity and chronicity in treatment-seeking adults

机译：寻求治疗的成年人共病注意缺陷多动障碍和物质使用障碍的复杂性和慢性

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Introduction and Aims. Attention deficit hyperactivity disorder (ADHD) is a known risk factor for substance use disorder (SUD); however, the potential additive contribution of comorbid ADHD to drug-specific dependence in SUD populations is largely unknown. The current study aimed to assess this association between ADHD symptoms and drug-specific SUD complexity and chronicity. Design and Methods. A cross-sectional survey was administered to a convenience sample of 489 adults receiving SUD treatment at 16 Australian drug and alcohol treatment centres between September 2010 and August 2011. Participants were screened for adult ADHD symptoms using the Adult ADHD Self-Report Scale. Associations between ADHD screening status and drug-specific SUD complexity and chronicity were assessed using multivariate logistic and modified Poisson regression analysis, controlling for a range of potential confounders. Results. Overall, 215 (44%) patients screened positive for concurrent adult ADHD and SUD. After Simes' correction, a significant positive association was observed between ADHD screening status and current amphetamine SUD (odds ratio (OR) = 1.85; 95% confidence interval (CI): 1.19-2.36). Patients who screened positive for ADHD were significantly more likely to report SUD history for heavy alcohol use (OR = 2.05; 95% CI: 1.21-3.45) and amphetamine (OR = 1.96; 95% CI: 1.26-3.06) as well as significantly increased risk of moderate (3-4 years) duration for benzodiazepine and amphetamine SUDs and long (>= 5 years) duration for alcohol, opiates other than heroin or methadone, and amphetamine SUDs. Discussion and Conclusions. The findings provide evidence that there is increased drug dependence complexity and chronicity in treatment-seeking SUD patients who screen positively for ADHD, specifically for amphetamine, alcohol, opiates other than heroin or methadone, and benzodiazepines.
机译：简介和目的。注意缺陷多动障碍（ADHD）是物质使用障碍（SUD）的已知危险因素。然而，共病多动症对SUD人群中药物特异性依赖性的潜在加性贡献尚不清楚。当前的研究旨在评估ADHD症状与药物特异性SUD复杂性和慢性之间的这种关联。设计和方法。在2010年9月至2011年8月之间，对在16个澳大利亚毒品和酒精治疗中心接受SUD治疗的489名成年人的便利性样本进行了横断面调查。使用成人ADHD自我报告量表对参与者的成人ADHD症状进行筛查。使用多元逻辑和改进的泊松回归分析评估了ADHD筛查状态与药物特异性SUD复杂性和慢性之间的关联，并控制了一系列潜在的混杂因素。结果。总体而言，有215例（44％）患者同时患有成人ADHD和SUD筛查为阳性。经过Simes校正后，观察到ADHD筛查状态与当前的苯丙胺SUD之间存在显着的正相关（比值比（OR）= 1.85; 95％置信区间（CI）：1.19-2.36）。筛查ADHD阳性的患者更有可能报告SUD有重度酒精使用史（OR = 2.05; 95％CI：1.21-3.45）和苯丙胺（OR = 1.96; 95％CI：1.26-3.06）以及苯二氮卓类和苯丙胺类SUDs的中度（3-4年）持续时间增加，酒精，海洛因或美沙酮以外的鸦片类药物和苯丙胺类SUDs的中度（3-4年）持续时间增加（> = 5年）。讨论和结论。该发现提供了证据，表明积极筛查ADHD（尤其是苯丙胺，酒精，除海洛因或美沙酮以外的鸦片类药物和苯二氮卓类药物）的寻求治疗的SUD患者，其药物依赖性的复杂性和慢性性增加。

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