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Microstructural Modelling and Performance Simulation of Engineered Bio-Composites

机译:工程生物复合材料的微观结构建模和性能模拟

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A primary goal in modern orthopaedics is increasing the rate and long-lasting anchoring of implants in the human body. Hydroxyapatite, having a chemical structure and chemistry that is identical to bone, significantly enhances the ongrowth and subsequent ingrowth of natural bone material. Nevertheless some aspects of the performance of hydroxyapatite coatings have not been investigated sufficiently; for example the in vivo, long-term behaviour of the material, including the time-dependent dissolution accompanied by changes of mechanical properties have been poorly documented. The current study creates an idealized, virtual microstructural coating model that examines the time-dependent behaviour and properties of hydroxyapatite coatings. The analyses examine time vs. dissolution dependencies that reflect in vivo behaviour.
机译:现代骨科的主要目标是提高植入物在人体中的固定率和持久性。具有与骨骼相同的化学结构和化学性质的羟基磷灰石显着增强了天然骨骼材料的向内生长和向后生长。然而,羟基磷灰石涂层性能的某些方面尚未得到充分研究。例如,材料的体内长期行为,包括随时间变化的溶出伴随着机械性能的变化,都鲜有文献记载。当前的研究创建了一个理想的虚拟微结构涂层模型,该模型检查了羟基磷灰石涂层随时间变化的行为和性能。该分析检查了反映体内行为的时间与溶出度的依赖关系。

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