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首页> 外文期刊>Drugs and aging >The medication appropriateness index at 20: Where it started, where it has been, and where it may be going
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The medication appropriateness index at 20: Where it started, where it has been, and where it may be going

机译：20岁时的药物适宜性指数：开始，去向和去向

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摘要

Potentially inappropriate prescribing for older adults is a major public health concern. While there are multiple measures of potentially inappropriate prescribing, the medication appropriateness index (MAI) is one of the most common implicit approaches published in the scientific literature. The objective of this narrative review is to describe findings regarding the MAI's reliability, comparison of the MAI with other quality measures of potentially inappropriate prescribing, its predictive validity with important health outcomes, and its responsiveness to change within the framework of randomized controlled trials. A search restricted to English-language literature involving humans aged 65+ years from January 1992 to June 2013 was conducted using MEDLINE and EMBASE databases using the search term 'medication appropriateness index'. A manual search of the reference lists from identified articles and the authors' article files, book chapters, and recent reviews was conducted to identify additional articles. A total of 26 articles were identified for inclusion in this narrative review. The main findings were that the MAI has acceptable inter- and intra-rater reliability, it more frequently detects potentially inappropriate prescribing than a commonly used set of explicit criteria, it predicts adverse health outcomes, and it is able to demonstrate the positive impact of interventions to improve this public health problem. We conclude that the MAI may serve as a valuable tool for measuring potentially inappropriate prescribing in older adults.
机译：潜在的不适当的老年人处方是主要的公共卫生问题。尽管有多种可能的不适当处方开具，但药物适宜性指数（MAI）是科学文献中最常见的隐式方法之一。这篇叙述性综述的目的是描述有关MAI可靠性的发现，MAI与可能不适当处方的其他质量指标的比较，其对重要健康结果的预测有效性以及其在随机对照试验框架内对变化的反应性。使用MEDLINE和EMBASE数据库，使用搜索词“药物适用性指数”，搜索了1992年1月至2013年6月65岁以上的英语文献。从已识别的文章以及作者的文章文件，书籍章节和最近的评论中手动搜索参考列表，以识别其他文章。总共确定了26篇文章要纳入此叙述性评论。主要发现是，MAI具有可接受的评分者间和评分者内部信度，与一组常用的明确标准相比，它更经常发现潜在的不适当处方，可以预测不良的健康结果，并且能够证明干预措施的积极影响改善这个公共卫生问题。我们得出的结论是，MAI可能是衡量老年人中潜在不适当处方的有价值的工具。

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