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首页> 外文期刊>JAIDS: Journal of acquired immune deficiency syndromes >Increased risk of tuberculosis with human T-lymphotropic virus-1 infection: a case-control study.
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Increased risk of tuberculosis with human T-lymphotropic virus-1 infection: a case-control study.

机译:人类T淋巴病毒1型感染增加了结核病的风险:一项病例对照研究。

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摘要

OBJECTIVES: To investigate whether infection with human T-lymphotropic virus type 1 (HTLV-1) increases the risk of tuberculosis. DESIGN: A case-control study. SETTING: City of Salvador, Brazil. PARTICIPANTS: A total of 375 patients with tuberculosis (cases) and 378 individuals without tuberculosis (controls), matched by age and sex. MAIN OUTCOME MEASURE: Tuberculosis of lung or lymph node. MAIN EXPOSURE: Human HTLV-1 infection. RESULTS: The prevalence of HTLV-1 infection was 4.27% (16/375) in patients with tuberculosis and 1.32% (5/378) in controls, resulting in a crude odds ratio of 3.31 (95% CI, 1.20-9.13) and an adjusted odds ratio of 3.01 (95% CI, 1.06-8.58). CONCLUSION: HTLV-1 infection is associated with a first diagnosis of tuberculosis. This may have implications for tuberculosis control in places with high prevalence of HTLV-1.
机译:目的:调查感染人1型T淋巴细胞病毒(HTLV-1)是否会增加结核病的风险。设计:病例对照研究。地点:巴西萨尔瓦多市。参与者:共有375名结核病患者(病例)和378名无结核病患者(对照),按年龄和性别匹配。主要观察指标:肺结核或淋巴结结核。主要接触:人HTLV-1感染。结果:结核病患者中HTLV-1感染的患病率为4.27%(16/375),对照人群中HTLV-1感染的患病率为1.32%(5/378),从而导致粗略的优势比为3.31(95%CI,1.20-9.13)和调整后的优势比为3.01(95%CI,1.06-8.58)。结论:HTLV-1感染与结核病的首次诊断有关。这可能对HTLV-1高发地区的结核病控制有影响。

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