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首页> 外文期刊>JACC. Cardiovascular imaging. >PET measurement of absolute myocardial blood flow and LV function in dilated cardiomyopathy.
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PET measurement of absolute myocardial blood flow and LV function in dilated cardiomyopathy.

机译：PET测量扩张型心肌病的绝对心肌血流量和LV功能。

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摘要

QUANTITATIVE POSITRON EMISSION TOMOGRAPHY (PET) imaging to assess absolute myocardial blood flow (mbf) is superior to standard stress/rest tracer uptake images for functional assessment of the coronary circulation (1) and in selected patients (e.g., renal insufficiency, low prior probability of coronary artery disease [CAD]) may provide an attractive alternative to coronary angiography to assess for CAD. PET measurements of absolute MBF provide detailed information concerning: 1) extent and functional severity of CAD (Fig. 1); 2) presence of uniform marked reduction in hyperemic response to adenosine (Fig. 2); and 3) evidence of coronary steal (Fig. 3), which is often associated with impaired regional contractile function (2). Moreover, electrocardiography gated images of the left ventricular (LV) myocardium can provide absolute measurements of LV volumes (Fig. 4) from which physiological parameters such as stroke work and power are derived. These indexes are essential to assessment of absolute values of MBF and provide important clinical information such as response to therapy in patients with dilated cardiomyopathy (DCM).
机译：用于评估绝对心肌血流（mbf）的定量正电子发射断层扫描（PET）成像优于标准应力/静止示踪剂摄取图像，可用于冠状动脉循环功能评估（1）和某些患者（例如，肾功能不全，先天性可能性低）冠状动脉疾病（CAD）的评估）可能为冠状动脉造影提供有吸引力的替代方法来评估CAD。绝对MBF的PET测量提供了有关以下方面的详细信息：1）CAD的程度和功能严重性（图1）; 2）对腺苷的充血反应均匀一致地明显减少（图2）; 3）冠状动脉盗窃的证据（图3），通常与区域收缩功能受损有关（2）。此外，左心室（LV）心肌的心电门控图像可以提供LV容积的绝对测量值（图4），从中可以得出生理参数，例如中风功和力量。这些指数对于评估MBF绝对值至关重要，并提供重要的临床信息，例如扩张型心肌病（DCM）患者对治疗的反应。

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