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首页> 外文期刊>JAMA facial plastic surgery >Biomechanical properties of superficial musculoaponeurotic system tissue with vs without reinforcement with poly-4-hydroxybutyric acid absorbable mesh
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Biomechanical properties of superficial musculoaponeurotic system tissue with vs without reinforcement with poly-4-hydroxybutyric acid absorbable mesh

机译:聚-4-羟基丁酸可吸收网片增强与不增强的浅表肌腱膜系统组织的生物力学特性

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IMPORTANCE It is unknown whether poly-4-hydroxybutyric acid (P4HB)-reinforced superficial musculoaponeurotic system tissue (SMAS) plication techniques will support SMAS imbrication and plication and potentially improve outcomes in rhytidectomy. OBJECTIVES To evaluate the biomechanical properties (tissue breaking strength, suture tearing force, and stress relaxation) of the SMAS with vs without reinforcement with P4HB absorbable mesh and to correlate these results with potential clinical applications. DESIGN, SETTING, AND SAMPLES In a cadaver study at an academic setting, 12 fresh frozen cadaver heads were used. Rhytidectomy incisions were made, and the SMAS was harvested and prepared for strength and stress testing using an Instron device. MAIN OUTCOMES AND MEASURES Tissue breaking strength and suture tearing force were analyzed. Stress relaxation test results were also assessed. The results of the SMAS samples alone were compared with those reinforced with P4HB absorbable mesh. RESULTS Overall, there were significant differences noted in tissue breaking strength and suture tearing force between the 2 groups. When the SMAS was reinforced with absorbable mesh, significant improvements were observed in tissue breaking strength (P < .001) and suture tearing force (P < .003). In addition, less variability was demonstrated in the maximum tensile load-bearing quality of the SMAS when the repair was reinforced with P4HB. CONCLUSIONS AND RELEVANCE Reinforcement with P4HB absorbable mesh improves tissue breaking strength and suture tearing force in cadaveric SMAS. It also reduces the variability in load vs displacement seen among samples tested. These data suggest that P4HB-reinforced SMAS imbrication would support higher loads and provide more consistent, long-lasting SMAS support among patients undergoing rhytidectomy. Further studies are needed to correlate these data with clinical outcomes in rhytidectomy.
机译:重要性聚-4-羟基丁酸(P4HB)增强的浅表肌腱膜系统组织(SMAS)褶皱技术是否会支持SMAS的褶皱和褶皱,并有可能改善除皱术的结局尚不明确。目的评估具有或不具有P4HB可吸收网片增强的SMAS的生物力学性能(组织断裂强度,缝合线撕裂力和应力松弛),并将这些结果与潜在的临床应用相关联。设计,设置和示例在学术机构的尸体研究中,使用了12个新鲜的冷冻尸体头。进行除皱术切口,并收获SMAS,并准备使用Instron设备进行强度和压力测试。主要结果和措施分析了组织断裂强度和缝线撕裂力。还评估了应力松弛测试结果。将仅SMAS样品的结果与用P4HB可吸收网增强的结果进行了比较。结果总体而言,两组之间在组织断裂强度和缝合线撕裂力方面存在显着差异。当SMAS用可吸收的网片增强时,组织断裂强度(P <.001)和缝线撕裂力(P <.003)明显改善。此外,当使用P4HB进行修补时,SMAS的最大拉伸承载质量的变异性较小。结论和相关性P4HB可吸收网片的加固可提高尸体SMAS的组织断裂强度和缝合线撕裂力。它也减少了在测试样品中看到的载荷与位移之间的差异。这些数据表明,P4HB增强的SMAS闭锁将支持更高的负荷,并在进行除皱术的患者中提供更一致,更持久的SMAS支持。需要进一步的研究以使这些数据与除皱术的临床结果相关联。

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