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首页> 外文期刊>JAMA neurology >A rare presentation of hypertrophic olivary degeneration secondary to primary central nervous system lymphoma
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A rare presentation of hypertrophic olivary degeneration secondary to primary central nervous system lymphoma

机译：原发性中枢神经系统淋巴瘤继发于肥厚性橄榄色变性的罕见表现

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A 71-year-old man presented with a 2-week history of nausea, vomiting, unsteady gait, and diplopia. Magnetic resonance imaging of the brain revealed a gadolinium-enhanced lesion involvingthesuperiorver-mis and the right middle cerebellar peduncle (Figure 1A and B). A biopsy was consistent with a high-grade B-cell lymphoma (Figure 2). Three months later, the patient was readmitted with difficulty walking, diplopia, loss of coordination, and slurring of speech. On examination, he had scanning dysarthric speech and palatal myoclonus (Video). An eye examination revealed right-sided gaze-evoked nystagmus and bilateral vertical pen-dular nystagmus in the primary position. Significant truncal ataxia was present. There was evidence of appendicular ataxia with dysmetria more noticeable on the right. Tone was more increased on the rightthan on the left, with spasticity mostly affecting the lower extremities.
机译：一名71岁的男子有2周的恶心，呕吐，步态不稳和复视史。脑部的磁共振成像显示involving累及上颌骨和右小脑中轴的病变（图1A和B）。活检与高度B细胞淋巴瘤一致（图2）。三个月后，患者因行走困难，复视，失去协调和言语不清而重新入院。检查时，他扫描了构音障碍性言语和pa肌阵挛（视频）。眼睛检查发现右侧凝视诱发的眼球震颤和双眼垂直笔状眼球震颤处于主要位置。存在明显的躯干共济失调。有证据显示，右肢共济失调伴子宫发育不良。右手的音调比左手的调高，痉挛主要影响下肢。

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