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Sclerosing sweat duct carcinoma of the eyelid

机译:眼睑硬化性汗管癌

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Background: Sclerosing sweat duct carcinoma (SSDC) is a rare variant of sweat gland carcinomas. We report a case of SSDC of the eyelid.Case: A 33-year-old woman presented with a painless, slowly enlarging nodule in her left lower eyelid. Incisional biopsy revealed proliferated ducts lined by two layers of epithelium embedded in a dense fibrous stroma. Cytologic atypia was not evident. Initial histopathological diagnosis was a syringoma or an inflammatory reaction.Observations: Four years after initial biopsy, the mass had enlarged slightly. Madarosis was observed thereafter. The lesion was excised completely with frozen section evaluation of the margins and repaired by a semicircular rotation flap. Microscopically, variable sized tubular structures could be seen invading the deep dermis and muscle. The final diagnosis was SSDC.Conclusions: This tumor is seldom recognized and is frequently confused with benign syringoma or inflammation. Wide and deep excisional biopsy is necessary for correct diagnosis and successful treatment. Jpn J Ophthalmol 2004;48:7-11 (C) Japanese Ophthalmological Society 2004.
机译:背景:硬化性汗管癌(SSDC)是汗腺癌的一种罕见变体。病例:一名33岁的女性左下眼睑出现无痛,缓慢扩大的结节。切开活检显示,增生的导管排列成两层上皮,其内嵌在致密的纤维基质中。细胞学上的异型性不明显。最初的组织病理学诊断为脊髓空洞或炎症反应。观察:首次活检后四年,肿块略有增大。此后观察到疟疾。用冷冻切片评估边缘完全切除病变,并用半圆形旋转瓣修复。在显微镜下,可以看到大小不同的管状结构侵入真皮和肌肉深处。最终诊断为SSDC。结论:该肿瘤很少被识别,并常与良性神经鞘瘤或炎症相混淆。广泛而深入的切除活检对于正确诊断和成功治疗是必要的。 Jpn J Ophthalmol 2004; 48:7-11(C)日本眼科学会2004。

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