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首页> 外文期刊>Japanese Journal of Ophthalmology >Association between clinical diagnostic tests and health-related quality of life surveys in patients with dry eye syndrome.
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Association between clinical diagnostic tests and health-related quality of life surveys in patients with dry eye syndrome.

机译：干眼综合征患者的临床诊断测试与健康相关的生活质量调查之间的关联。

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PURPOSE: This study was performed to assess the impact of dry eye on patients' quality of life (QOL) and to analyze the association between subjective symptoms and ocular surface findings of dry eye. METHODS: The study population consisted of 158 patients with dry eye aged 20 years or older who visited any of the 15 medical care facilities enrolled in the study. The backgrounds and ocular findings of the patients were investigated, and their QOL was evaluated with the Japanese version of the 25-item National Eye Institute Visual Functioning Questionnaire (VFQ-25) and of the Medical Outcomes Study (MOS) 8-item Short-Form Health Survey (SF-8) to examine the association between subjective symptoms and ocular surface findings. RESULTS: Of the patients enrolled, 15 were men and 143 were women, and their average age was 62.5 +/- 12.6 years. Sixty patients (38.0%) had comorbid Sjogren syndrome (SS). The results of Schirmer testing, fluorescein staining, and rose bengal staining for SS patients were significantly worse than those for the non-SS patients, but the VFQ-25 and SF-8 scores were not significantly different between the SS and non-SS patients. In the ocular surface findings, a weak association between the fluorescein staining scores and general vision scores, a subscale of the VFQ-25, was found. However, the ocular surface findings and VFQ-25/SF-8 results in the simple correlation analysis as well as in the multiple linear regression analysis showed no significant associations. CONCLUSIONS: Ocular surface findings and QOL scores of patients with dry eye appear to disagree. Therefore, it is necessary to address subjective symptoms and QOL scores in addition to examination findings when evaluating dry eye.
机译：目的：本研究旨在评估干眼症对患者生活质量（QOL）的影响，并分析干眼症的主观症状与眼表发现之间的关联。方法：研究人群包括158位20岁或20岁以上的干眼患者，他们访问了参与研究的15家医疗机构中的任何一家。调查了患者的背景和眼部检查结果，并用日文版25项国家眼科研究所视觉功能问卷（VFQ-25）和医学成果研究（MOS）的8项简短项目对他们的QOL进行了评估。形成健康调查表（SF-8），以检查主观症状与眼表发现之间的关联。结果：入组患者中，男性15例，女性143例，平均年龄为62.5 +/- 12.6岁。 60名患者（38.0％）患有合并干燥综合征（SS）。 SS患者的Schirmer检测，荧光素染色和玫瑰红染色结果明显差于非SS患者，但VFQ-25和SF-8评分在SS和非SS患者之间没有显着差异。在眼表发现中，发现荧光素染色评分与一般视力评分（VFQ-25的一个子量表）之间存在弱关联。但是，在简单的相关性分析以及多元线性回归分析中，眼表发现和VFQ-25 / SF-8结果均无显着相关性。结论：干眼患者的眼表发现和QOL评分似乎不同。因此，在评估干眼症时，除了检查结果外，还必须解决主观症状和QOL评分。

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