...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Circulation journal >Coronary flow reserve by contrast enhanced transesophageal coronary sinus Doppler measurements can evaluate diabetic microvascular dysfunction.
【24h】

Coronary flow reserve by contrast enhanced transesophageal coronary sinus Doppler measurements can evaluate diabetic microvascular dysfunction.

机译：通过对比增强的经食道冠状动脉窦多普勒测量冠状动脉血流储备可以评估糖尿病微血管功能障碍。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: This study was undertaken to investigate whether coronary flow reserve (CFR) using coronary sinus flow (CSF), which can be measured by transesophageal Doppler echocardiography (TEDE), especially when contrast enhanced, is useful in evaluating microvascular dysfunction in patients with diabetes mellitus (DM). METHODS AND RESULTS: CSF recordings using contrast enhanced TEDE were performed before and after adenosine triphosphate infusion (0.15 mg x kg(-1) x min(-1)) in 16 patients with type 2 DM and diabetic retinopathy and in 13 non-DM patients (control). Coronary angiography revealed normal epicardial coronary arteries. CFR was defined as the ratio of the antegrade flow velocity time integral in hyperemic conditions and basal levels. Clear envelopes of CSF were obtained in all DM patients using contrast-enhanced TEDE. CFR using CSF in the DM group was significantly decreased compared with the control group (1.4+/-0.4 vs 2.1+/-0.5, p<0.01), but there were no significant differences of age, ejection fraction, rate of hypertension and hypercholesterolemia between the 2 groups. Using 1.7 of CFR as the cut-off value, diabetic microvascular dysfunction could be detected with 82% sensitivity and 83% specificity. CONCLUSIONS: CFR calculated by CSF using contrast-enhanced TEDE may be useful for evaluating diabetic microvascular dysfunction.
机译：背景：本研究旨在探讨可通过经食道多普勒超声心动图（TEDE）进行测量的使用冠状窦流量（CSF）的冠状动脉血流储备（CFR），特别是在增强造影剂的情况下，是否可用于评估糖尿病患者的微血管功能障碍（DM）。方法和结果：16例2型DM和糖尿病性视网膜病变患者和13例非DM患者在三磷酸腺苷输注（0.15 mg x kg（-1）x min（-1）之前和之后）使用对比增强TEDE进行CSF记录。患者（对照）。冠状动脉造影显示正常的心外膜冠状动脉。 CFR定义为充血条件和基础水平下顺行流速时间积分的比率。使用对比增强的TEDE在所有DM患者中获得清晰的CSF包膜。与对照组相比，DM组使用CSF的CFR显着降低（1.4 +/- 0.4对2.1 +/- 0.5，p <0.01），但年龄，射血分数，高血压和高胆固醇血症没有显着差异。在两组之间。使用CFR的1.7作为临界值，可以检测到糖尿病微血管功能障碍，灵敏度为82％，特异性为83％。结论：由CSF使用对比增强的TEDE计算的CFR可能对评估糖尿病微血管功能障碍有用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号