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首页> 外文期刊>Circulation journal >Aortic Reservoir Function After Arterial Switch Operation in Elementary School-Aged Children
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Aortic Reservoir Function After Arterial Switch Operation in Elementary School-Aged Children

机译：小学学龄儿童动脉切换手术后的主动脉贮库功能

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Background After the arterial switch procedure, decreased distensibility of the aortic root has been reported, which means impaired aortic reservoir function of the coronary circulation, but there have been no reports regarding the relationship of this issue to myocardial perfusion. Therefore, in the present study the aortic reservoir function and coronary supply-demand balance were examined in patients after undergoing the arterial switch operation (ASO) around the time of entering elementary school.Methods and Results Diastolic runoff (DR), which is the percentage of diastolic blood flow to total cardiac output, was measured as the index of aortic reservoir function. The subendocardial viability ratio was investigated as the index of coronary supply-demand balance. In the patient group, the aortic root was dilated (p<0.000l) and distensibility was impaired (p<0.0001) in comparison with an age-matched control group. However, there was no difference between the 2 groups in DR or subendocardial viability ratio.Conclusions Coronary supply-demand balance was preserved in the pediatric ASO patients, despite the aortic root dysfunction. The preserved DR suggests that dilatation of the aorta compensates for aortic reservoir function. Because large artery dysfunction predicts future cardiovascular diseases, careful follow-up is crucial.
机译：背景技术在进行动脉转换手术后，已经报道了主动脉根的可扩张性降低，这意味着冠状动脉循环的主动脉储库功能受损，但是尚无关于该问题与心肌灌注之间关系的报道。因此，在本研究中，我们对入小学时进行了动脉切换手术（ASO）的患者进行了主动脉贮库功能和冠状动脉供需平衡的检查。方法与结果舒张径流（DR）是百分比测量舒张血流对总心输出量的变化作为主动脉贮库功能的指标。心内膜下生存力比作为冠脉供需平衡的指标。与年龄匹配的对照组相比，患者组的主动脉根扩张（p <0.000l），扩张性受损（p <0.0001）。然而，两组之间的DR或心内膜下生存率没有差异。结论尽管小儿主动脉根部功能障碍，小儿ASO患者仍能维持冠脉供需平衡。保留的DR提示主动脉扩张可补偿主动脉储层功能。由于大动脉功能障碍预示着将来的心血管疾病，因此认真的随访至关重要。

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