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New results on optimizing rooted triplets consistency

机译:优化生根三胞胎一致性的新结果

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A set of phylogenetic trees with overlapping leaf sets is consistent if it can be merged without conflicts into a supertree. In this paper, we study the polynomial-time approximability of two related optimization problems called the maximum rooted triplets consistency problem (MAxRTC) and the minimum rooted triplets inconsistency problem (MINRTI) in which the input is a set R of rooted triplets, and where the objectives are to find a largest cardinality subset of R which is consistent and a smallest cardinality subset of R whose removal from R results in a consistent set, respectively. We first show that a simple modification to Wu's Best-Pair-Merge-First heuristic Wu (2004) [38] results in a bottom-up-based 3-approximation algorithm for MAxRTC. We then demonstrate how any approximation algorithm for MINRTI could be used to approximate MAxRTC, and thus obtain the first polynomial-time approximation algorithm for MAxRTC with approximation ratio less than 3. Next, we prove that for a set of rooted triplets generated under a uniform random model, the maximum fraction of triplets which can be consistent with any phylogenetic tree is approximately one third. We then provide a deterministic construction of a triplet set having a similar property which is subsequently used to prove that both MAxRTC and MINRTI are NP-hard even if restricted to minimally dense instances. Finally, we prove that unless P = NP, MINRTI cannot be approximated within a ratio of c . ln n for some constant c > 0 in polynomial time, where n denotes the cardinality of the leaf label set of R.
机译:如果可以将它们合并而不会冲突成为超级树,则具有重叠叶集的一组系统发育树就是一致的。在本文中,我们研究了两个相关的优化问题的多项式时间逼近度,这两个问题是最大根三元组一致性问题(MAxRTC)和最小根三元组不一致问题(MINRTI),其中输入是一组根三元组R目的是分别找到R的最大基数子集和R的最小基数子集。我们首先表明,对Wu的“最佳-对-合并-优先”启发式法Wu(2004)[38]的简单修改导致针对MAxRTC的基于自底向上的3近似算法。然后,我们演示如何将MINRTI的任何近似算法用于近似MAxRTC,从而获得近似比小于3的MAxRTC的第一个多项式时间近似算法。接下来,我们证明对于在均匀条件下生成的一组三重根在随机模型中,可以与任何系统发育树一致的三元组的最大分数约为三分之一。然后,我们提供具有相似属性的三元组的确定性构造,随后将其用于证明MAxRTC和MINRTI都是NP硬的,即使仅限于最小密度的实例。最后,我们证明除非P = NP,否则MINRTI不能在c的比率内近似。在多项式时间内某个常数c> 0的ln n中,其中n表示R的叶子标签集的基数。

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