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Modeling the process of human body iron homeostasis using a variant of timed Petri nets

机译：使用定时Petri网的变体对人体铁稳态过程进行建模

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摘要

The body iron homeostasis is one of the most important processes in the human body. This complex process is not fully understood and until recently only some parts of it have been described in the literature. In our recent papers the main part of the process has been described and a model based on Petri net theory has been proposed. However, in this model any time dependencies occurring in the biochemical process have not been taken into account. In the present paper the model is enriched in the way that durations of biochemical reactions composing this process have been included into the model. A variant of Petri net where with each place a time interval is associated has been used in order to describe these dependencies. The time interval associated with a place corresponds to a time lag of biochemical conditions which must be fulfilled in order to enable a biochemical reaction to start.
机译：体内铁稳态是人体中最重要的过程之一。这个复杂的过程还没有被完全理解，直到最近文献中只描述了其中的某些部分。在我们最近的论文中，描述了过程的主要部分，并提出了基于Petri网理论的模型。但是，在该模型中，未考虑生化过程中发生的任何时间依赖性。在本文中，通过将组成该过程的生化反应的持续时间包括在模型中的方式来丰富模型。为了描述这些依赖性，使用了陪替氏网络的一种变体，其中每个地方都有一个时间间隔。与地点相关的时间间隔对应于生化条件的时滞，必须满足该时滞才能使生化反应开始。

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