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首页> 外文期刊>Circulation journal >Effect of intravenous propranolol on left ventricular apical ballooning without coronary artery stenosis (ampulla cardiomyopathy): three cases.
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Effect of intravenous propranolol on left ventricular apical ballooning without coronary artery stenosis (ampulla cardiomyopathy): three cases.

机译:静脉内普萘洛尔对无冠状动脉狭窄(壶腹型心肌病)的左心室根尖球囊扩张的影响:三例。

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摘要

The precise etiological basis of transient left ventricular apical ballooning without coronary artery stenosis (ampulla or so-called 'takotsubo' cardiomyopathy) remains unknown, so the present study examined the acute effects of intravenous propranolol (2-4 mg) in 3 female patients (age range, 61-76 years) with the condition. Although one patient who did not have any intraventricular pressure gradients showed no improvement in the electrocardiographic and left ventricular wall motion abnormalities, the other 2 patients, who had significant intraventricular pressure gradients, did show improvement. Dynamic intraventricular obstruction might play a role in maintaining apical ballooning, at least, in patients exhibiting an intraventricular pressure gradient.
机译:尚无冠状动脉狭窄(壶腹或所谓的“ takotsubo”型心肌病)的短暂性左室心尖球囊扩张的确切病因基础尚不清楚,因此,本研究在3名女性患者中检查了静脉使用普萘洛尔(2-4 mg)的急性作用(年龄范围(61-76岁)。尽管一位没有任何心室内压梯度的患者在心电图和左心室壁运动异常方面没有改善,但另外2位有显着的心室内压梯度的患者却有改善。至少在表现出脑室内压力梯度的患者中,动态脑室内阻塞可能在维持心尖气囊中起一定作用。

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