Differences in negative T waves between takotsubo cardiomyopathy and reperfused anterior acute myocardial infarction

KosugeM.; EbinaT.; HibiK.; IwahashiN.; TsukaharaK.; EndoM.; MaejimaN.; NagashimaZ.; SuzukiH.; MoritaS.; UmemuraS.; KimuraK.

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Differences in negative T waves between takotsubo cardiomyopathy and reperfused anterior acute myocardial infarction

机译：takotsubo心肌病和再灌注前急性心肌梗死之间负T波的差异

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Background: In both takotsubo cardiomyopathy (TC) and reperfused anterior acute myocardial infarction (AMI), negative T waves commonly appear on the ECG in the subacute phase. This study aimed to clarify the ECG differences between these diseases. Methods and Results: We compared the ECGs with the greatest amplitude of negative T wave from 34 patients with TC and 237 patients with a first reperfused anterior AMI who were admitted within 6 h of symptom onset and who had no abnormal Q-waves on discharge ECG. Time from symptom onset to recording the ECG did not differ between TC and anterior AMI (2.4±1.5 vs. 2.1±2.0 days, P=0.48). TC was associated with a greater maximal amplitude of negative T wave (1.00±0.44 vs. 0.79±0.46 mV, P=0.044), and a greater number of leads with negative T waves (9.5±1.0 vs. 6.0±2.1, P0.001). Negative T waves were consistently observed in leads-aVR and V4-6, whereas negative T waves were rare in lead V 1 in TC. Negative T waves in lead-aV R (ie, positive T waves in lead aVR) and no negative T waves in lead V1 identified TC with 94% sensitivity and 95% specificity, representing the highest diagnostic accuracy. Conclusions: During the subacute phase, deeper negative T waves were more frequently and broadly distributed, particularly around leads facing the apical region, in TC than in reperfused anterior AMI.

机译：背景：在takotsubo心肌病（TC）和再灌注前急性心肌梗死（AMI）中，亚急性期心电图上通常会出现负T波。本研究旨在阐明这些疾病之间的心电图差异。方法和结果：我们比较了34例TC患者和237例症状发作后6小时内入院且出院时无异常Q波的首次再灌注前AMI患者237例中最大T波负振幅的心电图。。从症状发作到记录心电图的时间在TC和前AMI之间没有差异（2.4±1.5天与2.1±2.0天，P = 0.48）。 TC与负T波的最大振幅更大有关（1.00±0.44 vs. 0.79±0.46 mV，P = 0.044），并且与负T波的引线数量更多（9.5±1.0 vs. 6.0±2.1，P < 0.001）。在aVR引线和V4-6引线中始终观察到负T波，而在TC中，在V 1引线中很少见到负T波。铅-aV R中的负T波（即铅aVR中的正T波）和铅V1中没有负T波将TC鉴定为94％的敏感性和95％的特异性，代表了最高的诊断准确性。结论：在亚急性期，与再灌注前部AMI相比，TC中更深的负T波更频繁，更广泛地分布，尤其是在面对根尖区域的导线周围。

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《Circulation journal》 |2012年第2期|共7页
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KosugeM.; EbinaT.; HibiK.; IwahashiN.; TsukaharaK.; EndoM.; MaejimaN.; NagashimaZ.; SuzukiH.; MoritaS.; UmemuraS.; KimuraK.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Acute myocardial infarction; Electrocardiogram; Takotsubo cardiomyopathy;

机译：急性心肌梗死;心电图;Takotsubo心肌病;

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1. Differences in negative T waves between takotsubo cardiomyopathy and reperfused anterior acute myocardial infarction [J] . KosugeM., EbinaT., HibiK., Circulation journal . 2012,第2期

机译：takotsubo心肌病和再灌注前急性心肌梗死之间负T波的差异
2. Differences in Negative T Waves Between Takotsubo Cardiomyopathy and Reperfused Anterior Acute Myocardial Infarction [J] . Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Circulation journal . 2012,第2期

机译：Takotubo心肌病和再灌注前急性心肌梗死之间的负T波的差异
3. Differences in ST-elevation and T-wave amplitudes do not reliably differentiate takotsubo cardiomyopathy from acute anterior myocardial infarction [J] . ParkkonenO., AllonenJ., VaaraS., Journal of Electrocardiology: An International Publication for the Study of the Electrical Activities of the Heart . 2014,第5期

机译：ST高程和T波振幅的差异不能可靠地将takotsubo心肌病与急性前壁心肌梗死区分开
4. Comparative studies of heart rate variability (HRV) using Holter-ECG-systems and high resolution ECG-systems in patients with acute myocardial infarction and dilatative cardiomyopathy and healthy volunteers [C] . Hoffmann, M., Heinke, . 1997

机译：使用Holter-ECG系统和高分辨率ECG系统对急性心肌梗死和扩张型心肌病患者和健康志愿者进行心率变异性（HRV）的比较研究
5. Sodium MRI techniques and applications to acute reperfused myocardial infarction. [D] . Constantinides, Chris Demetris. 2001

机译：钠MRI技术及其在急性再灌注心肌梗死中的应用。
6. Differences in negative T waves among acute coronary syndrome acute pulmonary embolism and Takotsubo cardiomyopathy [O] . Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, 2012

机译：急性冠状动脉综合征急性肺栓塞和Takotsubo心肌病之间的负T波差异
7. MODERATED EPOSTERS1385Longitudinal strain assessment in dilated cardiomyopathy patients using a novel accelerated DENSE sequence1407Simultaneous T1 and T2 cardiac quantification with CABIRIA: initial clinical experience1423Head-to-head comparison of acceleration algorithms in 4-dimensional flow CMR1502Left ventricular function and size evaluated by hybrid cardiac positron emission tomography-magnetic resonance: Intraindividual comparison of left ventricular ejection fraction and ventricular volumes derived by two modalities1510Left Atrium assessed by Cardiovascular Magnetic Resonance at 1.5 and 3 Tesla – age and gender effects1514Comparison of Free Breathing Cardiac MRI Radial technique to the Standard Multi breath-hold cine SSFP CMR technique for the assessment of LV Volumes and Function1536Self-navigated free-breathing isotropic 3D whole heart phase sensitive inversion recovery magnetic resonance without navigator for detection of myocardial infarction1547Assessment of Right Ventricular Strain Using Myocardial Deformation Recovery Semi Automated Technique: Initial Experience and Normal Values1586Tissue tracking myocardial deformation analysis and prediction of left ventricular remodeling in acute myocardial infarction1589Investigating strategies for optimal 31P MRS clinical cardiac at 3T: Initial Results1620Quantitative Criteria for the Diagnosis of the Congenital Absence of Pericardium by Cardiac Magnetic Resonance1632Widespread tissue injury during acute myocardial infarction: evidence from advanced CMR relaxometry1322Computed tomography coronary angiography verSus sTRess cArdiac magneTic rEsonance for the manaGement of sYmptomatic revascularized patients: a cost effectiveness study (STRATEGY study)1339Comparison of low- versus high-dose of gadobutrol for late gadolinium enhancement imaging at 1.5 Tesla: a clinical feasibility study1347Multi-parametric Cardiac Magnetic Resonance for Prediction of Cardiac Complications in Thalassemia Intermedia: a Prospective Multicenter Study1461Prognostic value of Cardiovascular Magnetic Resonance derived indexes of myocardial fibrosis in heart transplant recipients1523The role of CMR in the acute phase of hospitalization: changing paradigms1542Preoperative CMR-based score predict ventricular response after surgical left ventricular reconstruction in ischemic heart failure patients1555Excellent response rate to cardiac resynchronization therapy guided with magnetic resonance imaging1626The ECG as a predictor of arrhythmogenic substrate on Cardiac Magnetic Resonance Imaging in patients undergoing ablation for premature ventricular contractions1649Comparison of T1-mapping at 3.0T CMR and angiographic APPROACH score for area at risk assessment in ST-segment elevation myocardial infarction1340Pathological correlates of left bundle branch disease in patients with non-ischemic cardiomyopathy: a cardiovascular magnetic resonance study1342Myocardial remodelling and fibrosis in nonischaemic dilated cardiomyopathy: insights from cardiovascular magnetic resonance1411The association between fibrosis and contractile dysfunction in hypertrophic cardiomyopathy assessed by cardiovascular magnetic resonance1622Persistent myocardial inflammation due to intramyocardial haemorrhage in reperfused STEMI as a precursor to adverse LV remodelling - insights from multi-parametric mapping1566Semiquantitative analysis of low and high b value DWI for detecting myocardial edema in acute myocarditis1567Value of Cardiac MRI In Detecting Coronary Artery Disease In Newly Diagnosed Systolic Dysfunction1570Usefulness of cardiac magnetic resonance in tuberous sclerosis complex1578Papillary muscles offer further insight into hypertrophied hearts: a cardiovascular magnetic resonance study1627Diagnostic and clinical implications of CMR timing (early versus late) in patients with troponin positive acute coronary syndromes and unobstructed coronary arteries: Table 1. [O] . Upasana Tayal, Alexandros Kallifatidis, P. Garg, 2016

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Differences in negative T waves between takotsubo cardiomyopathy and reperfused anterior acute myocardial infarction

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