Predicting Atrial Fibrillation and Its Complications

Alonso Alvaro; Norby Faye L.

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Predicting Atrial Fibrillation and Its Complications

机译：预测心房颤动及其并发症

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Atrial fibrillation (AF) is a common cardiac arrhythmia associated with an increased risk of stroke and other complications. Identifying individuals at higher risk of developing AF in the community is now possible using validated predictive models that take into account clinical variables and circulating biomarkers. These models have shown adequate performance in racially and ethnically diverse populations. Similarly, risk stratification schemes predict incidence of ischemic stroke in persons with AF, assisting clinicians and patients in decisions regarding oral anticoagulation use. Complementary schemes have been developed to predict the risk of bleeding in AF patients taking vitamin K antagonists. However, major gaps exist in our ability to predict AF and its complications. Additional research should refine models for AF prediction and determine their value to improve population health and clinical outcomes, advance our ability to predict stroke and other complications in AF patients, and develop predictive models for bleeding events and other adverse effects in patients using non-vitamin K oral anticoagulants.

机译：心房颤动（AF）是常见的心律不齐，与中风和其他并发症的风险增加相关。现在，可以使用经过验证的预测模型来识别社区中发生AF的较高风险的个体，这些模型考虑了临床变量和循环生物标志物。这些模型在种族和种族多样化的人群中表现出足够的表现。同样，风险分层方案可预测房颤患者缺血性卒中的发生率，从而帮助临床医生和患者做出有关口服抗凝药物使用的决策。已经开发出补充方案来预测服用维生素K拮抗剂的AF患者的出血风险。但是，我们预测房颤及其并发症的能力存在重大差距。其他研究应完善房颤预测模型并确定其价值，以改善人群健康状况和临床结局，提高我们预测房颤患者中风和其他并发症的能力，并开发出使用非维生素的患者出血事件和其他不良反应的预测模型口服抗凝剂。

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《Circulation journal》 |2016年第5期|共6页
作者
Alonso Alvaro; Norby Faye L.;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Atrial fibrillation; Heart failure; Predictive models; Stroke;

机译：心房颤动;心力衰竭;预测模型;中风;

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专利

1. Incidence and predictors of pericardial effusion as an early complication of catheter ablation for atrial fibrillation: The Japanese Catheter Ablation Registry of Atrial Fibrillation (J-CARAF) [J] . Yuji Murakawa, Teiichi Yamane, Masahiko Goya, Journal of arrhythmia. . 2017,第5期

机译：心包积液作为心房纤颤导管消融的早期并发症的发生率和预测因素：日本房颤消融术注册中心（J-CARAF）
2. Letter by Apostolakis et al Regarding Article, "Renal Dysfunction as a Predictor of Stroke and Systemic Embolism in Patients With Nonvalvular Atrial Fibrillation: Validation of the R(2)CHADS(2) Index in the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study Cohorts" [J] . Apostolakis Stavros, Lane Deirdre A., Banerjee Amitava Circulation: An Official Journal of the American Heart Association . 2013,第11期

机译：Acostolakis等人关于文章的信，“肾功能障碍是非衰弱性心房颤动患者中风和全身栓塞的预测因子：验证R（2）牧草（2）指数在火箭AF中的指数（Rivaroxaban曾经每日，口服，与维生素K拮抗剂相比，直接因子XA抑制预防心房颤动中的中风和栓塞试验）和阿里亚（心房颤动的抗凝和危险因素）研究队列“
3. Predicting atrial fibrillation recurrence with circulating inflammatory markers in patients in sinus rhythm at high risk for atrial fibrillation: data from the GISSI atrial fibrillation trial [J] . Serge Masson, Aneta Aleksova, Chiara Favero, Heart . 2010,第23期

机译：房颤高风险窦性心律患者的循环炎症指标预测房颤复发：来自GISSI心房颤动试验的数据
4. Catheter Ablation of Atrial Fibrillation: What Are the Risks and Complications and How Do We Avoid Them? [C] . S. THEMISTOCLAKIS, A. BONSO, A. ROSSILLO International Workshop on Cardiac Arrhythmias . 2004

机译：导管消融心房颤动：风险和并发症是什么？我们如何避免它们？
5. Studies of Ablation Complications During the Treatment of Atrial Fibrillation. [D] . Quallich, Stephen. 2015

机译：心房颤动治疗期间消融并发症的研究。
6. Incidence and predictors of pericardial effusion as an early complication of catheter ablation for atrial fibrillation: The Japanese Catheter Ablation Registry of Atrial Fibrillation (J-CARAF) [O] . Yuji Murakawa, Teiichi Yamane, Masahiko Goya, 2017

机译：心包积液作为房颤导管消融的早期并发症的发生率和预测因素：日本房颤导管消融注册系统（J-CARAF）
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Predicting Atrial Fibrillation and Its Complications

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