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首页> 外文期刊>Circulation journal >Low-Risk Profile for Cardiovascular Disease and Mortality in Japanese
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Low-Risk Profile for Cardiovascular Disease and Mortality in Japanese

机译：日本人心血管疾病和死亡率的低风险档案

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Background Some studies focusing on low-risk profiles for cardiovascular disease have been reported in Western countries. Yet, few reports have examined, with substantial longevity, the low-risk profile for cardiovascular disease in the Japanese population. This study examines whether having a favorable risk factor profile yields lower all-cause mortality and whether the proportion of those with a low-risk profile is larger in the Japanese population.Methods and Results A total of 8,339 men and women aged 30-69 years without a history of cardiovascular diseases for 19 years, who had participated in the 1980 National Survey on Circulatory Disorders after being randomly selected from throughout Japan, were followed. Low risk was defined as having all of the following baseline characteristics: blood pressure (BP) <120/80mmHg; no antihypertensive medication; serum cholesterol 160-240 mg/dl (4.14-6.22 mmol/L); no history of diabetes; and non-smoker. The long-term mortality of the low-risk group was compared with that of others using the Cox proportional hazard model. The prevalence of low risk was 9.4% of all participants. The multivariate-adjusted hazard ratios for low-risk individuals compared with others were as follows: 0.33 (95%confidence intervals (CI), 0.15-0.74) for cardiovascular disease and 0.63 (95% CI, 0.46-0.88) for all-cause mortality. The most attributable risk factor for all-cause mortality was high BP (>120/80mmHg).Conclusion Japanese individuals with favorable cardiovascular disease risk profiles had lower mortality from cardiovascular disease and all-causes than those without.
机译：背景技术西方国家已经报道了一些针对心血管疾病低风险状况的研究。然而，很少有报道以相当长的寿命来研究日本人群中心血管疾病的低风险状况。这项研究调查了在日本人群中是否具有有利的危险因素特征可以降低全因死亡率，以及低风险特征因素所占的比例是否更大。方法和结果共有30339至30岁的8339名男性和女性随访了19年没有心血管疾病史的患者，他们是在整个日本随机选择后参加了1980年的全国循环系统疾病调查的。低风险定义为具有以下所有基线特征：血压（BP）<120 / 80mmHg;没有降压药;血清胆固醇160-240 mg / dl（4.14-6.22 mmol / L）;没有糖尿病史;和不吸烟者。使用Cox比例风险模型，将低危人群的长期死亡率与其他人群的长期死亡率进行了比较。低风险的患病率为所有参与者的9.4％。低风险个体与其他个体相比的多元调整风险比如下：心血管疾病为0.33（95％置信区间（CI），0.15-0.74），所有原因为0.63（95％CI，0.46-0.88）死亡。全因死亡率最高的危险因素是高BP（> 120 / 80mmHg）。结论具有良好心血管疾病风险特征的日本人比非全因原因的心血管疾病和全因死亡率低。

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