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首页> 外文期刊>Circulation journal >Beneficial Effect of Preinfarction Angina on In-Hospital Outcome is Preserved in Elderly Patients Undergoing Coronary Intervention for Anterior Acute Myocardial Infarction.
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Beneficial Effect of Preinfarction Angina on In-Hospital Outcome is Preserved in Elderly Patients Undergoing Coronary Intervention for Anterior Acute Myocardial Infarction.

机译:在接受冠状动脉介入治疗急性急性心肌梗死的老年患者中,可保留梗塞前心绞痛对住院结果的有益作用。

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Background Preinfarction angina improves survival after acute myocardial infarction (AMI) in nonelderly but not elderly patients in the thrombolytic era. However, it remains unclear whether preinfarction angina has a beneficial effect on clinical outcome in elderly patients undergoing percutaneous coronary intervention (PCI). Methods and Results The study group comprised 484 anterior AMI patients who were admitted within 24 h of onset and underwent emergency PCI. Patients were divided into 2 groups: those aged <70 years (nonelderly patients, n=290) and those aged >/=70 years (elderly patients, n=194). Angina within 24 h before AMI was present in 42% of nonelderly patients and in 37% of elderly patients. In nonelderly patients, preinfarction angina was associated with a lower in-hospital mortality rate (1% vs 7%, p=0.02). Similarly, in elderly patients, preinfarction angina was associated with a lower in-hospital mortality rate (6% vs 16%, p=0.03). Multivariate analysis showed that the absence of preinfarction angina was an independent predictor of in-hospital mortality in both nonelderly (odds ratio 4.20; 95% confidence interval (CI) 1.20-10.6; p=0.04) and elderly patients (odds ratio 3.04; 95%CI 1.06-18.1; p=0.04). Conclusions Angina within the 24 h before AMI is associated with better in-hospital outcomes in elderly and nonelderly patients. (Circ J 2005; 69: 630 - 635).
机译:背景溶栓时代,非老年患者(而非老年患者)在急性心肌梗死(AMI)后,梗塞前心绞痛可改善生存率。但是,尚不清楚梗塞前心绞痛是否对接受经皮冠状动脉介入治疗(PCI)的老年患者的临床结果产生有益影响。方法和结果该研究组包括484名前AMI患者,他们在发病后24小时内入院并接受了紧急PCI。患者分为两组:年龄<70岁的患者(非老年患者,n = 290)和年龄≥70岁的患者(老年患者,n = 194)。 42%的非老年患者和37%的老年患者出现AMI前24小时内的心绞痛。在非老年患者中,梗死前心绞痛的院内死亡率较低(1%对7%,p = 0.02)。同样,在老年患者中,梗死前心绞痛的院内死亡率较低(6%比16%,p = 0.03)。多因素分析表明,在非老年人(比值比为4.20; 95%置信区间(CI)为1.20-10.6; p = 0.04)和老年患者(比值比为3.04; 95)中,无梗死前心绞痛是院内死亡率的独立预测因子。 %CI 1.06-18.1; p = 0.04)。结论AMI前24小时内的心绞痛与老年和非老年患者的院内预后较好有关。 (Circ J 2005; 69:630-635)。

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