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首页> 外文期刊>Circulation journal >Urbanization, life style changes and the incidence/in-hospital mortality of acute myocardial infarction in Japan: Report from the MIYAGI-AMI Registry Study
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Urbanization, life style changes and the incidence/in-hospital mortality of acute myocardial infarction in Japan: Report from the MIYAGI-AMI Registry Study

机译：日本的城市化，生活方式变化和急性心肌梗死的发病率/院内死亡率：MIYAGI-AMI注册研究的报告

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Background: It remains to be examined whether urbanization and lifestyle changes are associated with the incidence and mortality from acute myocardial infarction (AMI) in Japan. Methods and Results: A total of 19,921 AMI patients (male/female 14,290/5,631) registered by the MIYAGI-AMI Registry Study from 1988 to 2009 were divided into 2 groups according to their residences; inside (urban area, n=7,316) and outside (rural area, n=11,402) of Sendai City. From 1988 to 2009, the incidence of AMI (/100,000 persons/year) increased more rapidly in the rural area (24.2 to 51.4) than in the urban area (31.3 to 40.8) (P<0.001), with rapid aging in both areas. Moreover, from 1998 to 2009, the age-adjusted incidence of AMI in young (<44 years) and middle-aged (45-64 years) male patients (both P<0.05) in the rural area increased significantly, along with a markedly increased prevalence of dyslipidemia (P<0.001). Although in-hospital mortality from AMI decreased in both areas over the last 20 years (both P<0.001), it remained relatively higher in female than in male patients and was associated with higher age of the onset, longer elapsing time for admission and lower prevalence of primary coronary intervention in female patients in both areas. Conclusions: These results demonstrate that urbanization and lifestyle changes have been associated with the incidence and mortality from AMI, although sex differences still remain to be improved.
机译：背景：在日本，城市化和生活方式的改变是否与急性心肌梗死（AMI）的发生率和死亡率有关是否有待研究。方法和结果：1988年至2009年，通过MIYAGI-AMI登记研究登记的19,921例AMI患者（男性/女性14,290 / 5,631）按居住地分为两组。仙台市的内部（城市地区，n = 7,316）和外部（农村地区，n = 11,402）。从1988年到2009年，农村地区（24.2至51.4）的AMI发生率（/ 100,000人/年）比城市地区（31.3至40.8）的增长更快（P <0.001），两个地区均迅速老龄化。此外，从1998年到2009年，农村地区年轻（<44岁）和中年（45-64岁）男性患者（均P <0.05）的年龄校正后AMI发生率显着增加，并且显着增加血脂异常患病率增加（P <0.001）。尽管在过去的20年中，这两个地区的AMI住院死亡率均下降了（均P <0.001），但女性仍然比男性高，并且与发病年龄的增加，入院时间的延长和入院时间的降低有关。在这两个地区的女性患者中，初次冠状动脉介入治疗的患病率。结论：这些结果表明，尽管性别差异仍有待改善，但城市化和生活方式的改变与AMI的发病率和死亡率有关。

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