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首页> 外文期刊>Circulation journal >Evaluation of arteriolar hyalinosis of the skin of patients with chronic congestive heart failure.
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Evaluation of arteriolar hyalinosis of the skin of patients with chronic congestive heart failure.

机译：慢性充血性心力衰竭患者皮肤小动脉透明质酸的评估。

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摘要

To investigate whether microvascular lesions are present in the skin of patients with chronic congestive heart failure (CHF), skin biopsies were performed at the time of cardiac catheterization, and the results were compared with control subjects. The diagnosis of CHF was done by cardiac catheterization with reference to the elevation of plasma levels of brain natriuretic peptide (BNP). Although the severity of arteriolar hyalinosis did not correlate with the New York Heart Association functional class, increased hyalinosis was found in skin biopsies from 17 of 20 patients with CHF, but in none of the 6 control subjects. These results indicate that microangiopathic alterations in arterioles may exist in patients with CHF and therapy for peripheral vascular remodeling might be considered for such patients.
机译：为了研究慢性充血性心力衰竭（CHF）患者皮肤中是否存在微血管病变，在进行心脏导管插入术时进行了皮肤活检，并将结果与​​对照组进行了比较。 CHF的诊断是通过心导管检查并参考脑钠肽（BNP）血浆水平的升高进行的。尽管小动脉透明质酸的严重程度与纽约心脏协会功能等级无关，但是在20名CHF患者中有17名皮肤活检发现透明质酸增加，但在6名对照受试者中均未发现。这些结果表明，患有CHF的患者可能存在小动脉微血管病变，并且可以考虑对此类患者进行周围血管重塑的治疗。

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