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首页> 外文期刊>Circulation journal >Pregnancy-related acute myocardial infarction in Japan: A review of epidemiology, etiology and treatment from case reports
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Pregnancy-related acute myocardial infarction in Japan: A review of epidemiology, etiology and treatment from case reports

机译：日本妊娠相关的急性心肌梗死：病例报告的流行病学，病因学和治疗方法综述

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Background: Pregnancy-related acute myocardial infarction (AMI) is uncommon, but can result in maternal and/or fetal death. This study retrospectively reviews pregnancy-related AMI reported from medical institutions in Japan. Methods and Results: ...We electronically or manually searched the literature for reports of pregnancy-related AMI between 1981 and 2011. In total, 62 patients were described and the numbers increased in accordance with the rising average age of the mothers. AMI occurred frequently in women aged 30-34 years (mean age, 33), in the third trimester and postpartum (n=11 and n=28, respectively). The prevalence of conventional risk factors was relatively low (n=21). On the other hand, 29 patients had obstetric and/or non-obstetric complications, and 24 received medication. Only 8 AMI were caused by atherosclerosis, while coronary dissection, thrombus and spasm were the cause in 14, 9 and 12 cases, respectively. All patients with atherosclerosis had conventional risk factors, and some patients with spasm had a history of smoking. Medication with ergot derivatives was associated mostly with spasm, whereas ritodrine was potentially related to dissection. Conclusions: The prevalence of pregnancy-related AMI in Japan seems lower than in Western countries, and the etiology differs considerably. However, as the trend of later childbearing continues, more pregnant women have more risk factors, complications, and require medication. Cardiologists and obstetricians must consider the increased risk of AMI.
机译：背景：妊娠相关的急性心肌梗塞（AMI）并不常见，但可能导致孕产妇和/或胎儿死亡。这项研究回顾性回顾了日本医疗机构报告的妊娠相关AMI。方法和结果：...我们以电子或人工方式搜索了1981年至2011年之间与妊娠有关的AMI的报道。总共描述了62例患者，并且随着母亲平均年龄的增长而增加。 AMI常见于30-34岁（平均年龄33），孕中期和产后的女性（分别为n = 11和n = 28）。常规危险因素的患病率相对较低（n = 21）。另一方面，有29例有产科和/或非产科并发症，有24例接受了药物治疗。动脉粥样硬化仅引起8例AMI，而14例，9例和12例分别是冠状动脉夹层，血栓和痉挛。所有的动脉粥样硬化患者都有常规的危险因素，有些痉挛的患者有吸烟史。麦角衍生物的药物治疗主要与痉挛有关，而利托君可能与解剖有关。结论：在日本，与妊娠相关的AMI的患病率似乎比西方国家低，并且病因学上也存在很大差异。但是，随着以后生育的趋势继续发展，更多的孕妇有更多的危险因素，并发症并需要药物治疗。心脏科医生和妇产科医生必须考虑增加AMI的风险。

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