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首页> 外文期刊>Circulation journal >Medium-term prognosis of young Japanese adults having acute myocardial infarction.
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Medium-term prognosis of young Japanese adults having acute myocardial infarction.

机译：日本年轻人急性心肌梗塞的中期预后。

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BACKGROUND: Data on the medium- and long-term prognosis of young Japanese patients with acute myocardial infarction (AMI) are still lacking. METHODS AND RESULTS: In the present study, 1,458 AMI patients were enrolled in the AMI-Kyoto Multi-Center Risk Study between January 2000 and December 2003. Of these, clinical characteristics and medium-term prognosis were retrospectively compared in 21 young patients < 40 years (young group), and 190 non-young patients 60-70 years old (non-young group) who could be followed after hospital discharge. The young group was all male and had higher prevalence of current smoking and greater body mass index, but previous myocardial infarction (MI) and hypertension were more prevalent in the non-young group. The young group had a higher prevalence of single-vessel disease and a lesser incidence of left circumflex coronary artery as the culprit lesion. The acquisition rates of Thrombolysis In Myocardial Infarction 3 flow after primary percutaneous coronary intervention didnot differ between the 2 groups, but the data of maximal creatine kinase was significantly higher in the young group. During the follow-up period (average 2.42 years for young, 2.37 years for non-young), survival and event-free survival rates and incidence of major adverse cardiac events (MACE) did not differ between the 2 groups. The predictor of MACE during follow-up period was the presence of multivessel disease in the young group, whereas the presence of multivessel disease, history of previous MI and longer hospitalization were the predictors of MACE in the non-young group. CONCLUSIONS: These results suggest that the medium-term prognosis in young AMI patients is comparable to that of non-young AMI patients in Japan.
机译：背景：日本年轻的急性心肌梗死（AMI）患者的中长期预后数据仍然缺乏。方法和结果：本研究从2000年1月至2003年12月，对1458例AMI患者进行了AMI-京都多中心风险研究。其中，回顾性比较了21名<40岁的年轻患者的临床特征和中期预后。年（年轻组），以及190名60-70岁的非年轻患者（非年轻组），他们可以在出院后进行随访。青年组均为男性，目前吸烟的患病率较高，体重指数较高，但以前的心肌梗塞（MI）和高血压在非青年组中更为普遍。青年组的单支血管疾病患病率较高，左旋支冠状动脉作为罪魁祸首的发病率较低。两组之间在原发性经皮冠状动脉介入治疗后，心肌梗塞3血流溶解的获得率没有差异，但年轻组中最大肌酸激酶的数据明显更高。在随访期间（年轻人平均为2.42岁，非年轻人平均为2.37岁），两组的生存率和无事件生存率以及主要不良心脏事件（MACE）的发生率无差异。随访期间，MACE的预测因素是年轻组中是否存在多支血管疾病，而非年轻组则是多发性疾病的存在，既往MI的病史和住院时间更长。结论：这些结果表明，年轻的AMI患者的中期预后与日本的非年轻AMI患者相当。

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