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New tools for diagnosing spondyloarthropathy.

机译:诊断脊椎病的新工具。

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Ankylosing spondylitis (AS) in its established and early forms accounts for more than 5% of all cases of chronic low back pain. Attention has focused recently on decreasing the time from symptom onset to the diagnosis of AS, which currently ranges from five to 10 years. An earlier diagnosis would lead to improved management, in particular thanks to the recent introduction and continuing development of biotherapies, such as TNFalpha antagonists, and new imaging techniques, including Doppler ultrasonography and magnetic resonance imaging have proved capable of detecting early signs of AS. Biotherapies not only improve the symptoms, but may also slow or halt the progression of the inflammatory lesions before the development of radiographic changes. Current criteria for AS (New York, Amor, and ESSG) are classification criteria that provide useful diagnostic orientation in clinical practice but have inadequate sensitivity for the diagnosis of recent-onset AS. Several groups have been working on means of improving the early diagnosis of AS. An algorithm for the early diagnosis of axial AS developed by Rudwaleit et al. needs to be confirmed by prospective studies. The Assessment of SpondyloArthritis international Society (ASAS) has just issued new diagnostic criteria for AS that performed well in a large cohort of patients with recent-onset low back pain.
机译:确立的早期形式的强直性脊柱炎(AS)占所有慢性下腰痛病例的5%以上。最近的注意力集中在减少从症状发作到诊断AS的时间上,该时间目前为5到10年。较早的诊断将导致改善的管理,尤其是由于最近引入并持续开发诸如TNFα拮抗剂之类的生物疗法,并且新的成像技术(包括多普勒超声检查和磁共振成像)已被证明能够检测AS的早期征象。生物疗法不仅可以改善症状,还可以在放射线照相变化发生之前减缓或阻止炎症性病变的进展。当前AS的标准(纽约,阿莫尔和ESSG)是分类标准,可在临床实践中提供有用的诊断方向,但对新近发作的AS的敏感性不足。几个小组一直在研究改善AS早期诊断的方法。 Rudwaleit等人开发的一种用于轴向AS早期诊断的算法。需要通过前瞻性研究来证实。国际脊柱关节炎评估(ASAS)刚刚发布了AS的新诊断标准,该标准在大量近期发作的下背痛患者中表现良好。

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