Is fibromyalgia a muscle disorder?

Le Goff P

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Is fibromyalgia a muscle disorder?

机译：纤维肌痛是一种肌肉疾病吗？

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The presence of abnormalities in fibromyalgia muscle using current methodological approaches is well established. The more serious abnormalities are demonstrated by histologic studies particularly on electron microscopy: disorganisation of Z bands and abnormalities in the number and shape of mitochondria. Biochemical studies and P 31 magnetic resonance spectroscopy show inconstant abnormalities of ATP and phosphocreatine levels. Mitochondrial abnormalities reduced capillary circulation and thickened capillary endothelium may result in decreased availability of oxygen and impaired oxidative phosphorylation as well as ATP synthesis. These abnormalities do not seem to be the consequences of the much-discussed deconditioning of muscles although these consequences are not well known. Further studies of energy metabolism of the muscle during exercise are needed.

机译：使用现有的方法学方法，在纤维肌痛肌肉中存在异常已得到充分证实。组织学研究特别是在电子显微镜下证实了更严重的异常：Z谱带混乱以及线粒体的数量和形状异常。生化研究和P 31磁共振波谱显示ATP和磷酸肌酸水平的异常异常。线粒体异常减少了毛细血管循环，并且毛细血管内皮增厚，可能导致氧气的利用率降低，氧化磷酸化以及ATP合成受损。尽管这些后果尚不为人所知，但这些异常似乎并不是人们广泛讨论过的肌肉退化的后果。在运动过程中需要进一步研究肌肉的能量代谢。

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《Joint, bone, spine :》 |2006年第3期|共4页
作者
Le Goff P;
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正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学）;
关键词
teratologic; Fibromyalgia; Myopathy; Muscles; Capillaries; 纤维肌痛; 肌; 毛细血管;

机译：teratologic;Fibromyalgia;Myopathy;Muscles;Capillaries;纤维肌痛;肌;毛细血管;

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1. The effect of fibromyalgia and widespread pain on the clinically significant temporomandibular muscle and joint pain disorders--a prospective 18-month cohort study. [J] . Velly AM, Look JO, Schiffman E, The journal of pain: official journal of the American Pain Society . 2010,第11期

机译：纤维肌痛和广泛疼痛对临床上重要的颞下颌肌肉和关节痛疾病的影响-一项为期18个月的前瞻性队列研究。
2. Chronic pain and difficulty in relaxing postural muscles in patients with fibromyalgia and chronic whiplash associated disorders. [J] . Elert J, Kendall SA, Larsson B, The Journal of rheumatology . 2001,第6期

机译：患有纤维肌痛和慢性鞭打相关疾病的患者的慢性疼痛和放松姿势肌肉的困难。
3. Muscle fatigue in fibromyalgia is in the brain, not in the muscles: A case-control study of perceived versus objective muscle fatigue [J] . BandakE., AmrisK., BliddalH., Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2013,第6期

机译：纤维肌痛的肌肉疲劳是在大脑中，而不是在肌肉中：知觉性和客观性肌肉疲劳的病例对照研究
4. MOLECULAR FINGERPRINTING OF THE INTERSTITIUM PROTEOME IN THE VASTUS LATERALIS MUSCLE IN WOMEN WITH FIBROMYALGIA COMPARED TO HEALTHY CONTROLS USING MD-LC-MS/MS [C] . Bijar Ghafouri, Maria Turkina, Nikolaos Christidis, International Mass Spectrometry Conference . 2018

机译：与使用MD-LC-MS / MS的健康对照相比，纤维肌痛的妇女颅外肌肉术中蛋白质蛋白质中的分子指纹纹理
5. Examining the Relationship of Posttraumatic Stress and Fibromyalgia among Women Veterans: Long Term Impact Posttraumatic Stress Disorder, Military Sexual Trauma, and Fibromyalgia Have on Quality of Life. [D] . Torres, Tamika. 2016

机译：研究女性退伍军人创伤后应激与纤维肌痛的关系：创伤后应激障碍，军事性创伤和纤维肌痛对生活质量的长期影响。
6. The Effect of Fibromyalgia and Widespread Pain on the Clinically Significant Temporomandibular Muscle and Joint Pain Disorders - A Prospective 18-Month Cohort Study [O] . Ana Miriam Velly, John O. Look, Eric Schiffman, -1

机译：纤维肌痛和普遍疼痛对临床显着的颞下颌肌肉和关节疼痛障碍的影响 - 一种未来的18个月队列研究
7. The Effect of Fibromyalgia and Widespread Pain on the Clinically Significant Temporomandibular Muscle and Joint Pain Disorders—A Prospective 18-Month Cohort Study [O] . Ana Miriam Velly, John O. Look, Eric Schiffman, 2010

机译：纤维肌痛和普遍疼痛对临床显着的颞下颌肌肉和关节疼痛障碍的影响 - 一个未来的18个月的队列研究

Is fibromyalgia a muscle disorder?

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