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首页> 外文期刊>Journal of Anatomy >Distribution of neurons expressing tyrosine hydroxylase in the human cerebral cortex.
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Distribution of neurons expressing tyrosine hydroxylase in the human cerebral cortex.

机译：表达酪氨酸羟化酶的神经元在人大脑皮质中的分布。

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Since the very first detailed description of the different types of cortical interneurons by Cajal, the tremendous variation in the morphology, physiology and neurochemical properties of these cells has become apparent. However, it still remains unclear whether all types of interneurons are present in all cortical areas and species. Here we have focused on tyrosine hydroxylase (TH)-immunoreactive cortical interneurons, which although only present in certain species, are particularly abundant in the human neocortex. We argue that this type of interneuron is more widespread in the human neocortex than in any other species examined so far and that, therefore, it is probably involved in a larger variety of cortical circuits. In addition, notable regional variation can be seen in relation to these interneurons. These differences further emphasize the variability in the design of microcircuits between cortical areas and species, and they probably reflect an evolutionary adaptation of cortical circuits to particular functions.
机译：自从Cajal对不同类型的皮质中间神经元进行了最详尽的描述以来，这些细胞的形态，生理学和神经化学特性的巨大变化就变得显而易见。然而，仍然不清楚所有皮质区域和物种中是否存在所有类型的中间神经元。在这里，我们集中于酪氨酸羟化酶（TH）-免疫反应性皮层间神经元，尽管它们仅存在于某些物种中，但在人类新皮层中尤其丰富。我们认为，迄今为止，这种类型的中间神经元在人类新皮层中的分布比在其他物种中更为广泛，因此，它可能参与了更多种类的皮层回路。此外，与这些中间神经元相关的区域变化明显。这些差异进一步强调了皮层区域和物种之间微电路设计的可变性，并且它们可能反映了皮层电路对特定功能的进化适应。

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