...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of anesthesia >Does the addition of magnesium to bupivacaine improve postoperative analgesia of ultrasound-guided thoracic paravertebral block in patients undergoing thoracic surgery?
【24h】

Does the addition of magnesium to bupivacaine improve postoperative analgesia of ultrasound-guided thoracic paravertebral block in patients undergoing thoracic surgery?

机译：布比卡因中镁的添加是否可以改善接受胸外科手术的患者的超声引导下胸椎旁阻滞的镇痛效果？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: Magnesium is a plentiful intracellular cation that has been reported to possess analgesic effect. The present study was aimed to see whether addition of magnesium to bupivacaine in thoracic paravertebral block (TPVB) improved the analgesic effect after thoracic surgery. Materials and methods: Fifty adult patients undergoing elective open thoracic surgery were divided into two equal groups. Group I received 12 ml of 0.5 % bupivacaine plus 0.9 % saline (3 ml) whereas Group II received 12 ml of 0.5 % bupivacaine plus 150 mg magnesium sulphate (in 3 ml 0.9 % saline) for TPVB. The following parameters were assessed: onset, dermatomal levels and duration of sensory block, duration of analgesia, visual analogue scale (VAS) for pain, postoperative intravenous morphine consumption, pulmonary function tests (peak expiratory flow rate [PEFR], forced expiratory volume in 1 s [FEV1] and forced vital capacity [FVC]) before and 24 h after surgery, and complications from the drugs and technique. Results: Group II patients showed a significantly longer sensory block duration (224.6 ± 59.3 vs 160.1 ± 55.2 min, P < 0.05), longer duration of analgesia (388.8 ± 70.6 vs 222.2 ± 61.6 min, P < 0.05), less VAS during the postoperative 48 h, less need for postoperative morphine (16.2 ± 7.4 vs 29.5 ± 11.1 mg, P < 0.05) and lower incidence of somnolence (0 [0 %] vs 5 [20 %], P < 0.05). Furthermore, postoperative pulmonary function tests (PEFR, FEV1 and FVC) were significantly better in Group II whereas there was no significant difference between both groups regarding the sensory block dermatomal level or hemodynamic data. Conclusion: Addition of magnesium to bupivacaine in TPVB improved the analgesic effect of bupivacaine in patients undergoing thoracic surgery.
机译：目的：镁是一种丰富的细胞内阳离子，据报道具有镇痛作用。本研究旨在观察在胸椎旁椎板阻滞（TPVB）中向布比卡因中添加镁是否能改善胸外科手术后的镇痛效果。材料和方法：将接受择期开胸手术的五十名成人患者分为两组。第一组接受12 ml 0.5％布比卡因加0.9％盐水（3 ml），而第二组接受12 ml 0.5％布比卡因加150 mg硫酸镁（在3 ml 0.9％盐水中）用于TPVB。评估以下参数：发作，皮肤水平和感觉阻滞持续时间，镇痛持续时间，疼痛的视觉模拟量表（VAS），术后静脉内吗啡消耗，肺功能检查（峰值呼气流速[PEFR]，强制呼气量）。 1 s [FEV1]和强制肺活量[FVC]）在手术之前和之后24 h，以及药物和技术引起的并发症。结果：第二组患者的感觉阻滞持续时间显着延长（224.6±59.3 vs 160.1±55.2 min，P <0.05），镇痛持续时间更长（388.8±70.6 vs 222.2±61.6 min，P <0.05），在手术期间VAS减少术后48小时，术后对吗啡的需求较少（16.2±7.4对29.5±11.1 mg，P <0.05），并且睡眠障碍的发生率较低（0 [0％]对5 [20％]，P <0.05）。此外，第二组的术后肺功能测试（PEFR，FEV1和FVC）明显更好，而在感觉阻滞性皮肤水平或血液动力学数据方面，两组之间无显着差异。结论：TPVB中布比卡因中添加镁可改善布比卡因对胸外科手术患者的镇痛作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号