Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling

Yang Xiangsheng; Wang Tiannan; Lin Xi; Yue Xiaojing; Wang Qiongling; Wang Guoliang; Fu Qin; Ai Xun; Chiang David Y.; Miyake Christina Y.; Wehrens Xander H. T.; Chang Jiang

首页> 外文期刊>Circulation research: a journal of the American Heart Association >Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling

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Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling

机译：Rnd3 / RhoE的基因删除通过蛋白激酶A信号上调导致小鼠心脏钙泄漏。

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Rationale: Rnd3, a small Rho GTPase, is involved in the regulation of cell actin cytoskeleton dynamics, cell migration, and proliferation. The biological function of Rnd3 in the heart remains unexplored.

机译：原理：Rnd3，一种小的Rho GTP酶，参与细胞肌动蛋白细胞骨架动力学，细胞迁移和增殖的调控。 Rnd3在心脏中的生物学功能尚未开发。

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《Circulation research: a journal of the American Heart Association》 |2015年第1期|共10页
作者
Yang Xiangsheng; Wang Tiannan; Lin Xi; Yue Xiaojing; Wang Qiongling; Wang Guoliang; Fu Qin; Ai Xun; Chiang David Y.; Miyake Christina Y.; Wehrens Xander H. T.; Chang Jiang;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
adrenergic receptor; beta-2; arrhythmias; cardiac; calcium; rho GTP-binding proteins; ubiquitination;

机译：肾上腺素能受体;β-2;心律不齐;心脏;钙;rho GTP结合蛋白;泛素化;

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1. Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling [J] . Yang Xiangsheng, Wang Tiannan, Lin Xi, Circulation research: a journal of the American Heart Association . 2015,第1期

机译：Rnd3 / RhoE的基因删除通过蛋白激酶A信号上调导致小鼠心脏钙泄漏。
2. Small GTPase RHOE/RND3, a new critical regulator of NF‐κB signalling in glioblastoma multiforme? [J] . Sun Qian, Dong Huimin, Li Yuntao, Cell Proliferation . 2019,第5期

机译：小GTPase rhoe / rnd3，胶质母细胞瘤的NF-κB信号传导的新临界调节器？
3. Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1α/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1α and Regulates Responsive Cardiac Angiogenesis [J] . Yue, Lin, Yang, Hypertension: An Official Journal of the American Heart Association . 2016,第3期

机译：Rnd3 / RhoE通过稳定低氧诱导因子1α调节低氧诱导因子1α/血管内皮生长因子信号传导并调节反应性心脏血管生成。
4. Involvement of protein kinases in the NaCl-induced upregulation of antioxidant enzyme activities in cotton callus [C] . D. R. Gossett, C. V. Orellana, S. W. Banks, Beltwide Cotton Conferences . 2002

机译：蛋白激酶参与NaCl诱导的棉花愈伤组织抗氧化酶活性的上调
5. Mitogen-activated protein kinases mediate angiotensin II-induced upregulation of AT1 receptors in the brain of heart failure rats . [D] . Wei, Shunguang. 2007

机译：丝裂原激活的蛋白激酶介导血管紧张素II诱导的心力衰竭大鼠脑中AT1受体的上调。
6. Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling [O] . Xiangsheng Yang, Tiannan Wang, Xi Lin, -1

机译：Rnd3 / RhoE结果通过蛋白激酶A信号上调在小鼠心脏钙泄漏中的遗传删除
7. Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling [O] . Xiangsheng Yang, Tiannan Wang, Xi Lin, 2015

机译：RND3 / rhoE的遗传缺失通过蛋白质激酶的上调发射信号来实现小鼠心脏钙渗漏
8. Protective Role of PI3-kinase/Akt/eNOS Signaling in Mechanical Stress Through Inhibition of p38 Mitogen-Activated Protein Kinase in Mouse Lung [R] . Peng, X., Damarla, M., Skirball, J., 2010

机译：pI3-激酶/ akt / eNOs信号通过抑制小鼠肺中p38丝裂素活化蛋白激酶对机械应激的保护作用

Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling

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