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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Digestion and absorption of ferulic acid sugar esters in rat gastrointestinal tract
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Digestion and absorption of ferulic acid sugar esters in rat gastrointestinal tract

机译：大鼠胃肠道中阿魏酸酯的消化吸收

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摘要

We estimated the absorption site and absorptivity of ferulic acid (FA) and its sugar esters, namely 5-O-feruloyl-L-arabinofuranose (FAA) and feruloyl-arabinoxylan (FAXn), in rats on the basis of their recovery in intestinal content and feces by comparing the values with those of a nonabsorbable marker, poly R-478. The results indicated that free FA was absorbed almost completely before reaching cecum. About 40% of dietary FAA was absorbed in rat foregut and 57% disappeared in the cecum. In contrast, about 67% of the FA moiety in FAXn was released and then disappeared predominantly in the hindgut. These results suggested that the existing form of FA in diets affects its absorptivity, its absorption site, and its ensuing fate in the gastrointestinal tract. Those ingested FAs esterified with saccharides; especially, polysaccharides have to transit the hindgut where FA might be released and then absorbed and/or degraded by microflora in lumen. Such microbial degradation may be an important factor affecting the bioavailability of dietary FA.
机译：我们根据大鼠肠内容物的恢复情况，估计了阿魏酸（FA）及其糖酯（即5-O-阿魏酰-L-阿拉伯呋喃糖（FAA）和阿魏酰-阿拉伯木聚糖（FAXn））的吸收部位和吸收率。通过将其值与不可吸收的标记poly R-478的值进行比较。结果表明，游离FA在到达盲肠之前几乎被完全吸收。约40％的饮食FAA在大鼠前肠中吸收，而57％在盲肠中消失。相反，FAXn中约67％的FA部分被释放，然后主要在后肠消失。这些结果表明，饮食中脂肪酸的现有形式会影响其在胃肠道中的吸收率，吸收位点以及随之而来的命运。那些摄入被糖酯化的脂肪酸的人。特别是多糖必须经过后肠，FA可能会释放出来，然后被管腔中的菌群吸收和/或降解。此类微生物降解可能是影响膳食FA生物利用度的重要因素。

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