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首页> 外文期刊>Journal of applied biological chemistry >Antioxidant and Anticancer Activities of Methanol and Water Extracts from Leaves of Cirsium japonicum
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Antioxidant and Anticancer Activities of Methanol and Water Extracts from Leaves of Cirsium japonicum

机译：枸杞叶片甲醇和水提取物的抗氧化和抗癌活性

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摘要

Potential antioxidant activities of methanol and water extracts of Cirsium japonicum var. ussuriense (CJ) leaves were examined. The reducing power and hydroxyl raical-scavenging activity assays showed that the methanol extract had a significantly higher activity than the water extract. In addition, the methanol extract showed a concentration-dependent reducing power, ranging from 0.228 to 1.072 (0.1-0.5 mg/mL), as well as a high DPPH free radical-scavenging activity (EC_(50)= 40.25mu g/mL). The totalphenolic (as tannic acid) and flavonoid (as quercetin) contents of the extract were 62.41 mg/g and 13.48 mg/g, respectively. The cytotoxic activity indicated that the methanol extract has an inhibition activity in the stomach carcinoma cell (35.40%), suggesting that the methanol extract of CJ leaves could be used as a potential source of pharmaceutical material.
机译：刺参甲醇和水提取物的潜在抗氧化活性。检验了乌苏里香（CJ）叶片。还原能力和羟基自由基清除活性试验表明，甲醇提取物的活性明显高于水提取物。此外，甲醇提取物显示出浓度依赖性的还原力，范围从0.228至1.072（0.1-0.5 mg / mL），并且具有较高的DPPH清除自由基活性（EC_（50）= 40.25mu g / mL） ）。提取物中的总酚（单宁酸）和类黄酮（槲皮素）含量分别为62.41 mg / g和13.48 mg / g。细胞毒活性表明甲醇提取物在胃癌细胞中具有抑制活性（35.40％），表明CJ叶的甲醇提取物可以用作潜在的药物原料。

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