• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of applied biological chemistry >Synthesis and Biological Activities of Aklyl Thiosulfi(o)nates
【24h】

Synthesis and Biological Activities of Aklyl Thiosulfi(o)nates

机译：炔丙基硫代（邻）酸酯的合成及生物活性

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Alkyl thiosulfi(o)nates, analogs of allyl-2-propene-l-thiosulfinate isolated from Allium sativum and having antibacterial activity, were chemically synthesized and their biological activities were investigated. Alkyl thiosulfinates were prepared by oxidation of corresponding disulfides with organic peroxy acid, while alkyl thiosulfonates could be obtained by oxidation of the alkyl thiosulfinates using sodium periodate. All synthetic thiosulfi(o)nates showed antibacterial activity against Staphy-lococcus aureus B33 and antifungal activitiy against Candida utilis ATCC42416. Further more synthetic alkyl thiosulfonates displayed antioxidant activity and have also prevention effect of platelet aggregation induced by collagen in rat.
机译：化学合成烷基硫代亚硫酸（o）烷基酯，这是从大蒜中分离得到的烯丙基-2-丙烯-1-硫代亚磺酸盐的类似物，具有抗菌活性，并对其生物学活性进行了研究。烷基硫代亚磺酸盐是通过用有机过氧酸氧化相应的二硫化物而制得的，而烷基硫代亚磺酸盐可通过用高碘酸钠氧化烷基硫代亚磺酸盐而制得。所有合成的硫代（o）酸酯均显示对金黄色葡萄球菌B33具有抗菌活性，对utilic Candida utilis ATCC42416具有抗真菌活性。另外，更多的合成烷基硫代磺酸盐显示出抗氧化活性，并且还具有预防胶原蛋白诱导的大鼠血小板聚集的作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号