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Physical Properties of Silk Fibroin/Chitosan Blend Films

机译:丝素蛋白/壳聚糖共混膜的物理性质

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摘要

Silk fibroinlchitosan blend films were exaIninedthrough IR spectroscopy to determine the conformational changes of silk fibroin. The effects of the fibroin/chitOsan blend ratios (chitosan content) on the physical and mechanical prop~rtieswere inve~- tigated to discover the feasibility of using these films as bio~edicalm!iterialssuchas artificial skin and wound dressing. The mechanical properties of the blend films containing 10-40% chitosan were found to be excellent.. The tensilestl:e~gt~, bre~ng elongatio~..an~Young's modulus were a~ectedby the chitosan~ontentsof the. films, WhICh were also .r~lated to the densIty an? degree of .swellIng.. !he <;o~fficI.entof water vapor permeab1lIty of the blend films Increased lInearly WIth the chItosan content, and the val.ues of 1000-2000 9 m"-2 day-J were comparable to those of commercial wound dressings. Silk fibroinlchitosan blend films had good oxygen and water vapor permeabilities, making them useful as biomaterials. In particular, the blend film containing 40-50% chitosan showed very high oxygen permeability.
机译:通过IR光谱检查丝纤蛋白壳聚糖共混物膜以确定丝纤蛋白的构象变化。研究了纤维蛋白/壳聚糖混合比(壳聚糖含量)对物理和机械性能的影响,以发现将这些膜用作生物材料如人造皮肤和伤口敷料的可行性。已发现含有10-40%壳聚糖的共混膜的机械性能优异。拉伸强度,断裂伸长率和杨氏模量受其壳聚糖含量的影响。胶片也与密度有关?混合膜的水蒸气透过率的溶胀度几乎提高了,与壳聚糖含量相比,其值在1000-2000 9 m“ -2 day-J时几乎是可比的。蚕丝纤维素壳聚糖共混薄膜具有良好的氧气和水蒸气渗透性,使其可用作生物材料,特别是包含40-50%壳聚糖的共混薄膜显示出很高的透氧性。

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