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Study on thermoplastic polyurethane/polypropylene (TPU/PP) blend as a blood bag material

机译:热塑性聚氨酯/聚丙烯(TPU / PP)共混物作为血袋材料的研究

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Blends with different ratios of thermoplastic polyurethane/polypropylene (TPU/PP) were prepared by melt mixing using an internal Haake mixer. Properties of the blends were investigated using SEM micrographs of cryo-fractures and measurement of the mechanical strength, water absorption, cell culture, and platelet adhesion in vitro tests, which were compared with those of PVC blood bags. The effect of the addition of the ethylene-vinyl acetate (EVA) copolymer on the TPU/PP blend properties was investigated. The results indicated that a TPU/PP/EVA = 80/20/5 blend can be used as a new blood bag material. It was observed that the blend is homogeneous with higher mechanical strength than that of the commercial PVC blood bag. This blend also showed a compatible cell response in contact with L929 fibroblast cells and fewer tendencies to interaction with platelets compared to the PVC blood bag. Although the blends were immissible and no chemical reaction at the interface could be found, the blood compatibility of the blends were improved. (C) 2003 Wiley Periodicals, Inc. [References: 27]
机译:通过使用内部Haake混合器进行熔融混合,可以制备具有不同比例的热塑性聚氨酯/聚丙烯(TPU / PP)的共混物。使用冷冻断裂的SEM显微照片研究掺混物的性能,并在体外测试中测量机械强度,吸水率,细胞培养和血小板粘附性,并将其与PVC血袋进行比较。研究了添加乙烯-乙酸乙烯酯(EVA)共聚物对TPU / PP共混物性能的影响。结果表明,TPU / PP / EVA = 80/20/5混合物可以用作新的血袋材料。观察到,该共混物是均质的,具有比商业PVC血袋更高的机械强度。与PVC血袋相比,这种混合物在与L929成纤维细胞接触时也显示出相容的细胞反应,并且与血小板相互作用的趋势更小。尽管掺混物是不允许的,并且在界面处未发现化学反应,但是掺混物的血液相容性得到了改善。 (C)2003 Wiley Periodicals,Inc. [参考:27]

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