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首页> 外文期刊>Journal of Applied Polymer Science >Preparation of amphiphilic chitosan and their antimicrobial activities
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Preparation of amphiphilic chitosan and their antimicrobial activities

机译：两亲性壳聚糖的制备及其抗菌活性

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摘要

Two anionic soluble monomers, mono(2-methacryloyl oxyethyl)acid phosphate and vinylsulfonic acid sodium salt, were grafted onto chitosan to obtain copolymers zwitterionic property. Graft reaction improved the antimicrobial activities of chitosan. Antimicrobial activities of chitosan and graft copolymers depended largely on the amount and type of grafted chains as well as changes of pH, against Candida albicans, Trichophyton rubrum, and Trichophyton violaceum. The most excellent antimicrobial activity among tested samples was shown at pH 5.75 with demonstrating strain selectivity against Candida albicans and Trichophyton violaceum due to the difference in affinity between cell wall of fungi and chitosan or its derivatives.
机译：将两种阴离子可溶单体，单（2-甲基丙烯酰氧基乙基）酸磷酸酯和乙烯基磺酸钠盐接枝到壳聚糖上以获得共聚物的两性离子性质。接枝反应提高了壳聚糖的抗菌活性。壳聚糖和接枝共聚物的抗微生物活性主要取决于接枝链的数量和类型以及对白色念珠菌，毛癣菌和紫毛癣菌的pH值的变化。在测试样品中，最优异的抗菌活性显示在pH 5.75上，这表明由于真菌细胞壁与壳聚糖或其衍生物之间的亲和力不同，菌株对白色念珠菌和紫色毛癣菌的选择性也很高。

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