...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of applied toxicology >Decreased serum testosterone levels in rats exposed intraperitoneally to bismuth subnitrate.
【24h】

Decreased serum testosterone levels in rats exposed intraperitoneally to bismuth subnitrate.

机译：腹膜内暴露于亚硝酸铋的大鼠血清睾丸激素水平降低。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The consumption of bismuth is increasing and knowledge of the potential teratogenic and reproductive damage of bismuth exposure is fragmentary. In the present study we used autometallography (AMG)--the histochemical silver amplification technique--to trace bismuth in the testis and pituitary glands of Wistar rats injected intraperitoneally with bismuth subnitrate. Large amounts of bismuth AMG grains were concentrated in the lysosomes of Leydig cells, and serum testosterone levels were reduced when compared with controls. No histochemical traces of bismuth were found in the anterior lobe of the pituitary gland. Compared with their corresponding controls, neither follicle-stimulating hormone nor luteinizing hormone were affected. The selective uptake of bismuth in Leydig cells, followed by decreased testosterone levels, emphasizes a potential hazard of bismuth-provoked male reproductive impairment. Copyright 2002 John Wiley & Sons, Ltd.
机译：铋的消耗量在增加，对铋的潜在致畸和生殖损害的了解是零碎的。在本研究中，我们使用自动金相学（AMG）（组织化学银放大技术）追踪腹膜内注射亚硝酸铋的Wistar大鼠睾丸和垂体中的铋。与对照组相比，大量的铋AMG晶粒集中在Leydig细胞的溶酶体中，血清睾丸激素水平降低。在垂体前叶中未发现铋的组织化学痕迹。与相应的对照组相比，促卵泡激素和促黄体生成素均未受影响。睾丸间质细胞选择性吸收铋，然后降低睾丸激素水平，强调了铋诱发的男性生殖功能障碍的潜在危险。版权所有2002 John Wiley＆Sons，Ltd.

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号