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首页> 外文期刊>Journal of applied toxicology >Cytogenetic monitoring of cardiology unit hospital workers exposed to Doppler ultrasound.
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Cytogenetic monitoring of cardiology unit hospital workers exposed to Doppler ultrasound.

机译：心脏病部门医院工作人员暴露于多普勒超声的细胞遗传学监测。

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摘要

We studied the effects of ultrasound on the peripheral blood lymphocytes of medical personnel from a cardiology unit working with colour Doppler ultrasonic equipment. Cytogenetic risks from ultrasound exposure were assessed by analysis of chromosome aberrations, sister chromatid exchanges (SCE), study of cell-cycle kinetics and micronucleus assay. We found significant increases (P < 0.001) in the total number of chromosome aberrations, mainly due to chromatid breaks and acentric fragments, increases in the total number of micronuclei and SCE and disturbances in cell-cycle kinetics in the exposed group compared to the control. In spite of their limitations, the results of the present investigation indicate that individuals occupationally exposed to ultrasound may experience an increased genotoxic risk and strongly emphasize the need for more research into the nature and extent of the biological consequences to medical personnel working with Doppler ultrasound. Copyright 2000 John Wiley & Sons, Ltd.
机译：我们研究了使用彩色多普勒超声设备的心脏病科的超声对医务人员外周血淋巴细胞的影响。通过分析染色体畸变，姐妹染色单体交换（SCE），研究细胞周期动力学和微核分析来评估超声暴露引起的细胞遗传学风险。我们发现，与对照组相比，染色体畸变总数的显着增加（P <0.001），主要是由于染色单体断裂和无心性片段，微核和SCE总数的增加以及暴露组细胞周期动力学的紊乱所致。 。尽管存在局限性，但本研究的结果表明，职业性暴露于超声的个体可能会遭受更高的遗传毒性风险，并强烈强调需要进一步研究对使用多普勒超声的医务人员的生物学后果的性质和程度。版权所有2000 John Wiley＆Sons，Ltd.

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