首页> 外文期刊>Journal of biological inorganic chemistry: JBIC: a publication of the Society of Biological Inorganic Chemistry >Metals in medicine: metal-related diseases-Gold-coated maghemite nanoparticles for magnetic delivery of antitumor platinum(II) complexes
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Metals in medicine: metal-related diseases-Gold-coated maghemite nanoparticles for magnetic delivery of antitumor platinum(II) complexes

机译:医药中的金属:与金属有关的疾病-用于抗肿瘤铂(II)配合物磁性递送的金涂层磁赤铁矿纳米颗粒

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摘要

The magnetic nanoparticles represent one of the crucial possibilities of the targeted drug delivery, because their therapeutic application could reduce the chemotherapeutic dose and consequently also negative side effects connected with the drug application. The pharmacologically perspective systems should meet several requirements, such as easy and reproducible preparation with good yields, an effective response to the external magnetic field, high stability and drug release, non-toxicity and significant therapeutic action.
机译:磁性纳米颗粒代表了靶向药物递送的关键可能性之一,因为它们的治疗应用可以减少化学治疗剂量,因此也减少与药物应用相关的副作用。药理学角度的系统应满足几个要求,例如容易且可重复的高产量制备,对外部磁场的有效响应,高稳定性和药物释放,无毒和显着的治疗作用。

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